dentify the chiral centers in the following molecule and label each as R or S. HO H. O IlIl

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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**Problem 4: Identification of Chiral Centers**

**Objective:** Identify the chiral centers in the given molecular structure and label each as R or S.

**Instructions for Students:**

- Examine the structural formula provided. 
- Identify all the carbon atoms that are chiral centers.
- Determine the configuration (R or S) for each chiral center based on the CIP (Cahn-Ingold-Prelog) priority rules.

**Chemical Structure:**

The molecular structure is a complex, multi-ring compound with several chiral centers. Key features of the molecule include:

- Multiple cyclohexane rings with various substituents.
- Oxygen-containing functional groups, such as ketones and hydroxyls.
- Chiral centers, indicated by wedge and dash lines, representing bonds that are coming out of or going into the plane of the paper.

**Guidance on Identifying Chiral Centers:**

1. **Locate Tetrahedral Carbons:** Identify carbon atoms bonded to four different groups.
2. **Assign Priorities:** Use the CIP rules where higher atomic numbers get higher priority.
3. **Determine Configuration:**
   - Look from the least-priority group.
   - If the order of the remaining groups is clockwise, assign R (Rectus).
   - If counterclockwise, assign S (Sinister).

Students should carefully analyze each ring and substituent to accurately identify and label the chiral centers. Understanding stereochemistry is crucial for this task.
Transcribed Image Text:**Problem 4: Identification of Chiral Centers** **Objective:** Identify the chiral centers in the given molecular structure and label each as R or S. **Instructions for Students:** - Examine the structural formula provided. - Identify all the carbon atoms that are chiral centers. - Determine the configuration (R or S) for each chiral center based on the CIP (Cahn-Ingold-Prelog) priority rules. **Chemical Structure:** The molecular structure is a complex, multi-ring compound with several chiral centers. Key features of the molecule include: - Multiple cyclohexane rings with various substituents. - Oxygen-containing functional groups, such as ketones and hydroxyls. - Chiral centers, indicated by wedge and dash lines, representing bonds that are coming out of or going into the plane of the paper. **Guidance on Identifying Chiral Centers:** 1. **Locate Tetrahedral Carbons:** Identify carbon atoms bonded to four different groups. 2. **Assign Priorities:** Use the CIP rules where higher atomic numbers get higher priority. 3. **Determine Configuration:** - Look from the least-priority group. - If the order of the remaining groups is clockwise, assign R (Rectus). - If counterclockwise, assign S (Sinister). Students should carefully analyze each ring and substituent to accurately identify and label the chiral centers. Understanding stereochemistry is crucial for this task.
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There are six chiral centers in the molecules.

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