Define SIADH and discuss the pathophysiology and its impact on hyponatremia

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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8) Define SIADH and discuss the pathophysiology and its impact on hyponatremia

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Syndrome of inappropriate antidiuretic hormone ADH release (SIADH) is a disorder characterised by the persistent action of antidiuretic hormone (ADH) on vasopressin receptors or its unsuppressed release from the pituitary gland or nonpituitary sources.

SIADH is characterized by impaired water excretion leading to hyponatremia with hypervolemia or euvolemia. The causes, symptoms, and diagnosis of SIADH are reviewed in this activity, which also emphasises the management of the condition by the interprofessional team.

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