Considering that calcium and ATP are required for muscle contraction, what might explain why calcium inhibits pyruvate dehydrogenase kinase (PDHK) activity in muscle cells, but stimulates pyruvate dehydrogenase phosphatase- 1 (PDHP-1) activity? Calcium inhibition of PDHP-1 and stimulation of PDHK results in unphosphorylated active PDH and more ATP for muscle contraction. Calcium inhibition of PDHK and stimulation of PDHP-1 results in unphosphorylated active PDH and more ATP for muscle contraction. Calcium inhibition of PDHK and stimulation of PDHP-1 results in phosphorylated active PDH and more ATP for muscle contraction. Calcium inhibition of PDHK and stimulation of PDHP-1 results in unphosphorylated active PDH and more ADP for muscle contraction.

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