Consider a population of 150 mice on an island, with allele frequencies B = 0.20 for brown coat colour, and b = 0.80 for white coat colour. Brown (B) is dominant to white (b) and the population is in Hardy-Weinberg equilibrium. Twenty-five homozygous brown mice from the mainland float to the island on an uprooted tree after a storm.  What are the genotype frequencies before migration?  What are the allele frequencies after migration?  Now, suppose the twenty-five brown mice float away again on another tree without breeding, and the island is back to its original state. Allele frequencies on the island are back to B = 0.20, b = 0.80. On the continent, there is a large population of many thousands of mice, with allele frequencies B = 0.80, b = 0.20. One year, human ships begin moving back and forth between the island and the continent, and occasionally a mouse comes along for the ride, and stays and breeds. Equal numbers of mice ride in each direction. The shipping trade continues indefinitely. Where will the allele frequencies ultimately stabilize and why? (Assume that no other forces are affecting allele frequencies.)

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Consider a population of 150 mice on an island, with allele frequencies B = 0.20 for brown coat colour, and b = 0.80 for white coat colour. Brown (B) is dominant to white (b) and the population is in Hardy-Weinberg equilibrium. Twenty-five homozygous brown mice from the mainland float to the island on an uprooted tree after a storm.

    1.  What are the genotype frequencies before migration?
    2.  What are the allele frequencies after migration?
    3.  Now, suppose the twenty-five brown mice float away again on another tree without breeding, and the island is back to its original state. Allele frequencies on the island are back to B = 0.20, b = 0.80. On the continent, there is a large population of many thousands of mice, with allele frequencies B = 0.80, b = 0.20. One year, human ships begin moving back and forth between the island and the continent, and occasionally a mouse comes along for the ride, and stays and breeds. Equal numbers of mice ride in each direction. The shipping trade continues indefinitely. Where will the allele frequencies ultimately stabilize and why? (Assume that no other forces are affecting allele frequencies.)
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