Consider a cohort study to compare the mortality rate of myocardial infarction (MI) in men with sedentary work (exposed group) to men with physically active work (unexposed). If in the exposed, there were 36,000 person (man) years of observation and 126 deaths whereas the unexposed had 24,000 man-years of observation and 44 deaths.            Compute the following a) Mortality rate in each cohort? b) What is the relative risk of dying, comparing these 2 groups? c) What is the attributable risk of sedentary work?

Linear Algebra: A Modern Introduction
4th Edition
ISBN:9781285463247
Author:David Poole
Publisher:David Poole
Chapter7: Distance And Approximation
Section7.3: Least Squares Approximation
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Consider a cohort study to compare the mortality rate of myocardial infarction (MI) in men with sedentary work (exposed group) to men with physically active work (unexposed). If in the exposed, there were 36,000 person (man) years of observation and 126 deaths whereas the unexposed had 24,000 man-years of observation and 44 deaths.

           Compute the following

  1. a) Mortality rate in each cohort?
  2. b) What is the relative risk of dying, comparing these 2 groups?
  3. c) What is the attributable risk of sedentary work?
  4. d) What is the attributable benefit of physical activity?
  5. e) If we assume that MI is associated with the mortality in this cohort (causality), what proportion of the disease in the higher group is potentially preventable?
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