i just need the second box **Intramolecular Aldol Reaction Mechanism**Complete the mechanism for the intramolecular aldol reaction shown below. Add the missing curved arrow notation, lone pair electrons, and nonzero formal charges to all boxes. The reaction requires a base (e.g., NaOH) but we will ignore the Na⁺ because it does not participate in the mechanism. Do not add any other reagents.**18th Attempt**The mechanism is illustrated through a series of four structural diagrams representing different stages of the intramolecular aldol reaction.1. **First Diagram**: - A structure with a benzene ring attached to a chain with a carbonyl group is shown. - There are no curved arrows, lone pairs, or charges indicated.2. **Second Diagram**: - A similar structure is depicted, but the arrangement indicates a change in bonding likely illustrating deprotonation or bond formation. - Curved arrows representing electron flow and lone pair electrons should be added to demonstrate the reaction step accurately.3. **Third Diagram**: - A ring structure is formed, indicating the progress towards cyclization. - Appropriate curved arrows should be added to show the intramolecular interaction leading to ring closure.4. **Fourth Diagram**: - The final product is shown with two newly formed rings, completing the aldol reaction. - The box is labeled "Et₃b," possibly referencing a base or catalyst involved.The flow and transformations in these diagrams provide a visual representation of the intramolecular aldol condensation mechanism. Understanding and correctly depicting each transition state with curved arrows and lone pair electrons are crucial for mastering organic reaction mechanisms.

An arrow always depicts from a region of high electron density to low electron density ; that is tail depicts region of high electron density and head depicts region of low electron density.This is aldol condensation reaction, a type of nucleophilic addition reaction.In first step, proton abstraction by hydroxide base takes place.The intermediate enolate is formed.This undergoes intramolecular nucleophilic attack at aldehyde to form tetrahedral intermediate.Proton transfer by solvent water takes place to form aldol.Again Proton abstraction by Hydroxide base takes place followed by loss of Hydroxide to form final product.This is E1CB mechanism.Lone pair & negative charge has to be shown on carbanion (Alpha carbon).

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Complete the mechanism for the intramolecular aldol reaction shown below. Add the missing curved arrow notation, lone pair electrons, and nonzero formal charges to all boxes. The reaction requires a base (eg, NaOH) but we will ignore the Na* because it does not participate in the mechanism. Do not add any other reagents. 18th attempt que var se Eige See Periodic Table Eich

Complete the mechanism for the intramolecular aldol reaction shown below. Add the missing curved arrow notation, lone pair electrons, and nonzero formal charges to all boxes. The reaction requires a base (eg, NaOH) but we will ignore the Na* because it does not participate in the mechanism. Do not add any other reagents. 18th attempt que var se Eige See Periodic Table Eich

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter13: Substitution

Section: Chapter Questions

Problem 13E

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Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.

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i just need the second box

**Intramolecular Aldol Reaction Mechanism**

Complete the mechanism for the intramolecular aldol reaction shown below. Add the missing curved arrow notation, lone pair electrons, and nonzero formal charges to all boxes. The reaction requires a base (e.g., NaOH) but we will ignore the Na⁺ because it does not participate in the mechanism. Do not add any other reagents.

**18th Attempt**

The mechanism is illustrated through a series of four structural diagrams representing different stages of the intramolecular aldol reaction.

1. **First Diagram**:
- A structure with a benzene ring attached to a chain with a carbonyl group is shown.
- There are no curved arrows, lone pairs, or charges indicated.

2. **Second Diagram**:
- A similar structure is depicted, but the arrangement indicates a change in bonding likely illustrating deprotonation or bond formation.
- Curved arrows representing electron flow and lone pair electrons should be added to demonstrate the reaction step accurately.

3. **Third Diagram**:
- A ring structure is formed, indicating the progress towards cyclization.
- Appropriate curved arrows should be added to show the intramolecular interaction leading to ring closure.

4. **Fourth Diagram**:
- The final product is shown with two newly formed rings, completing the aldol reaction.
- The box is labeled "Et₃b," possibly referencing a base or catalyst involved.

The flow and transformations in these diagrams provide a visual representation of the intramolecular aldol condensation mechanism. Understanding and correctly depicting each transition state with curved arrows and lone pair electrons are crucial for mastering organic reaction mechanisms.

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