Column A Column B 1. the part of the antibody that binds | antigen a. light chain b. hypervariable region c. constant region 2. contributes around 50 kDa to the overall molecular weight of IgG 3. comprises the B strands and loops | not involved in antigen binding | 4. the most conserved region of the d. heavy chain molecule with limited variation between antibodies e. framework region 5. located within a V domain and var- ies greatly between different antibodies f. V domain 6. pairs with the amino-terminal part of a heavy chain to form one of the two arms of an antibody

Column A Column B 1. the part of the antibody that binds | antigen a. light chain b. hypervariable region c. constant region 2. contributes around 50 kDa to the overall molecular weight of IgG 3. comprises the B strands and loops | not involved in antigen binding | 4. the most conserved region of the d. heavy chain molecule with limited variation between antibodies e. framework region 5. located within a V domain and var- ies greatly between different antibodies f. V domain 6. pairs with the amino-terminal part of a heavy chain to form one of the two arms of an antibody

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter45: Defenses Against Disease

Section: Chapter Questions

Problem 5TYK

See similar textbooks

Similar questions

A dendritic cell engulfs a bacterium, then present bacterial bits on its surface along with a(n) _____. a. MHC marker b. antibody c. T cell receptor d. antigen
Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b. fever f. complement activation c. histamines g. presenting antigen d. cytokines h. all take part
A dendritic cell engulfs a bacterium, then present bacterial bits on its surface along with a(n) _____. a. MHC marker b. antibody c. T cell receptor d. antigen
pathogenic bacteria in gut lumen binds binds capture and transfer to A B submucosa inhibits binds produces produces epithelial cells of small intestine klocated below B-cll follicle in Peyer's patches reside on reside presents among antigens E F capture and transfer from lumen presents engulf antigens pathogenic bacteria in gut submucosa D -lyse-
eds Antibodies (Immunoglobulins) Objective 14 Antibodies (immunoglobulins) are glycoproteins secreted by plasma cells. They are located in interstitial fluid, plasma (gamma globulin fraction) and in body secretions. onse A. Antibody Structure Heavy chain Antigen-binding site Light chain Insmakamos Hinge region Complement- binding site Stem region Macrophage binding site OHO (a) Antibody molecule OHO X = Disulfide bond Carbohydrate four polypeptide chains (two heavy, two light) chains are held together by covalent disulfide bonds (S=S) each heavy chain and each light chain has two functional areas: consists of highly variable amino acid sequences which forms the basis of antibody specificity; antigen binds here ????? to more conserved amino acid sequences; there are five basic sequences of amino acids, which define the 5 antibody classes (IgG, IgA, IgM, IgE and IgD); ????? each class has its own characteristic set of effector functions (see next page) Your notes: 4 40 4. 39
Some Type-II immunopathology mediated autoimmune diseases have manifestations inmultiple different organs. Discuss how antibodies to one single antigen can cause damage inmultiple sites throughout the body. Things you might discuss include, but are not limited towhere the antigen could be expressed, how antibodies are made, how they bind antigen,where they circulate, the ratios of antigen to antibody, mechanisms of the immune systemthat result in cellular/tissue damage, or how immune system components can affect otherorgans. You might also comment on what makes one antigen an attractive target rather thananother. Please do NOT comment on all the things listed above, they are just to get youthinking. If you are having trouble getting started, it might help to think about a specificdisease which affects multiple organs.
Clear my choice Two antibodies, one is IgM and the other is IgG, both can bind to the same epitope. Which of the following is true about them? O a. They have almost same variable regioi and almost same constant region of the heavy chain. O b. They have almost same variable region but different constant region of the heavy chain. O c. They have different variable region and different constant region of the heavy chain. O d. They have different variable region but same constant region of the heavy chain. SLE is a. Cell mediated autoimmune disease.
Circulation in blood Immunocompetent, but still naive, lymphocyte migrates via blood A B C D E B D Immature lymphocytes D B [Choose ] [Choose ] [Choose ] [Choose ] [Choose ] [Choose ]
cella which wnsuld trigger If an antigen piesenting cel is presenting antigens fram an extracellular colonizer. you would expect to see more development of Oa Tu1 cel-mediated OET1 humoral Oc T2, humcral Od. T2, colmediated QUESTION 27 Which type of vaccine typically ptaduces the longest immunity sgainist a toxin? Oa toxoid Ob attenuated OG subunit Od.conjugated QUESTION 28 Which of the following is NOT a job far a TH1 cell? O a. Stimulate cytotaxic T cells Ob Simu ate natural killer cells to kill more effectively. Oc. StimulateB cell activation Od. Stimulate macrophages and neutrophits to mare effective at killing intracellutar pathogenn
DRAW IT Sketch a B cell antigen receptor. Label the Vand C regions of the light and heavy chains. Label theantigen-binding sites, disulfide bridges, and transmembrane region. Where are these features located relativeto the V and C regions?
Identify the highlighted part of the antibody O Antigen Binding Site O Constant region O Constant region of a heavy chain O Constant region of a light chain O Disulfide bond O Heavy chain O Light Chain O Variable region O Variable region of a heavy chain O Variable region of a light chain
1.A given B cell expresses only maternally or paternally derived heavy chains but never both. This observation is the result of A. antibodydiversity.B. isotypeswitching.C. allelicexclusion.D. affinitymaturation.E. randomVJgenerearrangement. 2.Which of the following antibody classes or isotypes facilitate the sequential binding of the C1, C4, C2, and C3 components of the complement system? A. IgAandIgD B. IgAandIgE C. IgDandIgM D. IgE and IgG E. IgMandIgG