Please help, I keep getting this question wrong-classify the two groups attached to the ring in salicylamide as activators ordeactivators. Then classify the directing effects of the two groups. thanks in advance Synthesis of lodosalicylamide - An Electrophilic AromaticSubstitutionIntroductionBenzene can undergo certain types of reactions known as electrophilic aromatic substitutions(EAS). As the name implies, some atom or small molecule substitutes onto the benzene ring inplace of a hydrogen atom. In today's experiment, we will be using a derivative of benzene,salicylamide, and substituting an iodine atom onto the ring. In all EAS reactions, the ring is thenucleophile while the atom/molecule that is being substituted onto the ring must haveelectrophilic character.Groups already present on the ring can either activate or deactivate the ring. Another way tothink about this is that activating groups can speed up the rate of reaction while deactivatinggroups slow down the reaction. Activating groups will donate electron density into the ring andwill specifically activate it's ortho and para positions. This is why we classify them as ortho, paradirectors. Deactivating groups will withdraw electron density from the ring. This electronwithdrawing effect deactivates the ortho para positions towards nucleophilic attack, which inturn directs the substitution to its meta position. This is why deactivating groups are metadirectors. The only exception to this statement is the halogens. The halogens do deactivate thering, but they also can donate an electron pair into the ring via resonance. Therefore, halogenswill be ortho para directing but deactivate the ring. Your organic lecture textbook and yourinstructor will have discussed this in further detail in lecture. More resources regarding thesetypes of reactions can be found under this week's resources on Brightspace.The overall reaction is shown below. The line going through the benzene ring connected toiodine is a type of shorthand that can be used when you're unsure of the exact location of thesubstituent on the ring. As far as the exact location of the substitution, you'll need to predictbased on your knowledge of the types of activating/deactivating groups already substituted onsalicylamide.NH₂OH1)Nal, NaOCI, CH CH.OH2) NaySO HCLNH₂OHAs a quick reference, the mechanism for the electrophilic aromatic substitution is shown belowThe electrophile, It, is generated from 12. The nucleophile, the pi electrons of the ring, attacks Iand loses aromaticity, forming a sigma complex. This sigma complex is a resonance stabilizedcarbocation intermediate. The ring will then regain aromaticity once it is deprotonated by abase. 08-6-3-6sigma complexDuring this reaction, a series of three redox reactions will take place. Color changes of thereaction mixture will be observed as the different redox reactions take place. In the first redoxreaction, the iodide ion (from Nal) reacts with hypochlorite in the presence of three protons toform iodine (12). 12 is the source of I*, the electrophile in the EAS reaction. Some of the iodide ionis left behind and will combine with 12 which forms la. The thiosulfate ion is then added toreduce la to water soluble 1¹ which stops the reaction.Redox Reactions:(1) CIO¹+ 41¹³ + 3H→ HCI +H₂O + 2 12 (red)1₂ +1¹²¹13¹¹ (yellow/green)13 +25₂03 → 31¹ +OS-S-S-SO(2)(3)Our reactant and product this week can be analyzed by investigating the fingerprint region ofthe IR. Substitution pattern on aromatic rings can be found in the region between 700 and 900cm depending on how the groups are arranged. You should be able to determine thesubstitution pattern of your product easily by examining this region. The vibration arises fromthe C-H bend from the aromatic ring called the "C-H oop." The different substitution patternsand their corresponding expected peaks are listed below.715-770 (strong)730-770 (strong)750 790 (strangho od760-820 (strong)800-850 (strong)830-910 (strong)800-870 (strong)

In the given question we have to identify the activating and deactivating groups and whether the…

Answered: classify the two groups attached to the…

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...