CI Assume the partition coefficient for this compound is too high. Propose a structural modification that would lower the partition coefficient, while not breaking the rules (Lipinski's rules)for total numbers of hydrogen bond donors/acceptors or the rule for molecualar weight.
CI Assume the partition coefficient for this compound is too high. Propose a structural modification that would lower the partition coefficient, while not breaking the rules (Lipinski's rules)for total numbers of hydrogen bond donors/acceptors or the rule for molecualar weight.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:N.
CI
Assume the partition coefficient for this
compound is too high. Propose a structural
modification that would lower the partition
coefficient, while not breaking the rules
(Lipinski's rules)for total numbers of hydrogen
bond donors/acceptors or the rule for
molecualar weight.
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