Chymotrypsin, trypsin, and elastase are digestive enzymes called serine proteases. The serine proteases differ in sub specificity. Chymotrypsin cleaves peptide bonds after aromatic or bulky hydrophobic side chains, trypsin requires ba acid residues, and elastase cleaves bonds following small uncharged side chains. A chart of amino acids is available your reference. Determine which specificity pocket is a part of each enzyme. Chymotrypsin Trypsin Elastase

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Q20:

Which amino acids have side chains that fit into the specificity pocket of elastase?
glycine
aspartate
alanine
lysine
tyrosine
arginine
Transcribed Image Text:Which amino acids have side chains that fit into the specificity pocket of elastase? glycine aspartate alanine lysine tyrosine arginine
Chymotrypsin, trypsin, and elastase are digestive enzymes called serine proteases. The serine proteases differ in substrate
specificity. Chymotrypsin cleaves peptide bonds after aromatic or bulky hydrophobic side chains, trypsin requires basic amino
acid residues, and elastase cleaves bonds following small uncharged side chains. A chart of amino acids is available for
your reference.
Determine which specificity pocket is a part of each enzyme.
Chymotrypsin
Trypsin
Answer Bank
Which amino acids have side chains that fit into the specificity pocket of elastase?
Elastase
Transcribed Image Text:Chymotrypsin, trypsin, and elastase are digestive enzymes called serine proteases. The serine proteases differ in substrate specificity. Chymotrypsin cleaves peptide bonds after aromatic or bulky hydrophobic side chains, trypsin requires basic amino acid residues, and elastase cleaves bonds following small uncharged side chains. A chart of amino acids is available for your reference. Determine which specificity pocket is a part of each enzyme. Chymotrypsin Trypsin Answer Bank Which amino acids have side chains that fit into the specificity pocket of elastase? Elastase
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