chronic-stable angina begins taking metoprolol

Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter9: Instrumentation In Blood Circulation
Section: Chapter Questions
Problem 4P
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A patient with chronic-stable angina begins taking metoprolol, and once blood levels reach the therapeutic range the frequency and severity of angina attacks and the need for sublingual nitroglycerin were reduced. Which of the following states the direct pharmacologic action by which the beta-blocker produced the desired effects?

  1. Decreased myocardial oxygen demand
  2. Dilated coronary vasculature
  3. Directly inhibited angiotensin II synthesis
  4. Reduced total peripheral resistance
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