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Choose the statements that best describe the findings based on the graph presented. Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes. There is an inverse relationship between size of the trisomic chromosome and the length of embryonic development. The longer the mice developed, the larger their chromosomes became. There is a positive correlation between size of the trisomic chromosome and the length of embryonic development. Choose the best possible explanation for these results. Being trisomic for larger chromosomes affects the dosage of more genes and is more detrimental, causing development to cease at an earlier stage. Larger chromosomes cause a more rapid onset of chromosomal instability than smaller chromosomes, which leads to earlier death during embryonic development. Being trisomic for smaller chromosomes is less detrimental because a smaller chromosome has less of a chance to develop a lethal mutation. Being trisomic for larger chromosomes causes an imbalance in the number of nucleotide bases normally found in

Choose the statements that best describe the findings based on the graph presented. Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes. There is an inverse relationship between size of the trisomic chromosome and the length of embryonic development. The longer the mice developed, the larger their chromosomes became. There is a positive correlation between size of the trisomic chromosome and the length of embryonic development. Choose the best possible explanation for these results. Being trisomic for larger chromosomes affects the dosage of more genes and is more detrimental, causing development to cease at an earlier stage. Larger chromosomes cause a more rapid onset of chromosomal instability than smaller chromosomes, which leads to earlier death during embryonic development. Being trisomic for smaller chromosomes is less detrimental because a smaller chromosome has less of a chance to develop a lethal mutation. Being trisomic for larger chromosomes causes an imbalance in the number of nucleotide bases normally found in

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Using breeding techniques, Andrei Dyban and V.S. Baranov created mice that were trisomic for each of the different mouse chromosomes (Cytogenetics of Mammalian Embryonic Development. Oxford: Oxford University Press,Clarendon Press; New York: Oxford University Press, 1987). They found that only mice with trisomy 19 developed fully. Mice trisomic for all other chromosomes died during development. For some of these trisomics, they compared the length of development, before the embryo died, as a function of the size of the chromosome that was present in three copies. This data is presented in the graph (E. Torres, B. R. Williams, and A. Amon. 2008. Genetics 179:737–746, Fig. 2B.). 2.5 Chr 1 2.0 Chr 6 1.5 Chr 13 Chr 14 Chr 10 1.0 Chr 12 Chr 16 Chr 18 0.5 0.0 11 12 13 14 15 16 17 18 Length of embryonic development (days) Size of mouse chromosomes (108 bp)
Transcribed Image Text:Using breeding techniques, Andrei Dyban and V.S. Baranov created mice that were trisomic for each of the different mouse chromosomes (Cytogenetics of Mammalian Embryonic Development. Oxford: Oxford University Press,Clarendon Press; New York: Oxford University Press, 1987). They found that only mice with trisomy 19 developed fully. Mice trisomic for all other chromosomes died during development. For some of these trisomics, they compared the length of development, before the embryo died, as a function of the size of the chromosome that was present in three copies. This data is presented in the graph (E. Torres, B. R. Williams, and A. Amon. 2008. Genetics 179:737–746, Fig. 2B.). 2.5 Chr 1 2.0 Chr 6 1.5 Chr 13 Chr 14 Chr 10 1.0 Chr 12 Chr 16 Chr 18 0.5 0.0 11 12 13 14 15 16 17 18 Length of embryonic development (days) Size of mouse chromosomes (108 bp)
Choose the statements that best describe the findings based on the graph presented. Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes. There is an inverse relationship between size of the trisomic chromosome and the length of embryonic development. The longer the mice developed, the larger their chromosomes became. There is a positive correlation between size of the trisomic chromosome and the length of embryonic development. Choose the best possible explanation for these results. Being trisomic for larger chromosomes affects the dosage of more genes and is more detrimental, causing development to cease at an earlier stage. Larger chromosomes cause a more rapid onset of chromosomal instability than smaller chromosomes, which leads to earlier death during embryonic development. Being trisomic for smaller chromosomes is less detrimental because a smaller chromosome has less of a chance to develop a lethal mutation. Being trisomic for larger chromosomes causes an imbalance in the number of nucleotide bases normally found in the nucleus. Question Source: Pierce 6e - Genetics: A Conceptual Approach |
Transcribed Image Text:Choose the statements that best describe the findings based on the graph presented. Mice trisomic at small chromosomes survived longer than mice trisomic at larger chromosomes. There is an inverse relationship between size of the trisomic chromosome and the length of embryonic development. The longer the mice developed, the larger their chromosomes became. There is a positive correlation between size of the trisomic chromosome and the length of embryonic development. Choose the best possible explanation for these results. Being trisomic for larger chromosomes affects the dosage of more genes and is more detrimental, causing development to cease at an earlier stage. Larger chromosomes cause a more rapid onset of chromosomal instability than smaller chromosomes, which leads to earlier death during embryonic development. Being trisomic for smaller chromosomes is less detrimental because a smaller chromosome has less of a chance to develop a lethal mutation. Being trisomic for larger chromosomes causes an imbalance in the number of nucleotide bases normally found in the nucleus. Question Source: Pierce 6e - Genetics: A Conceptual Approach |
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