The image depicts a chemical reaction involving multiple steps: 1. **Reactants (on the left side):** - A pyridine ring with a pendant amine group (NH). - A chloroformate moiety (COCl) with a protected hydroxyl group (OBn). - A vinyl silane group (OTMS). 2. **Reaction Conditions:** - The reaction is carried out in tetrahydrofuran (THF) as the solvent. - The temperature is initially between -78 to 0 degrees Celsius. - In the second step, the mixture is stirred for 1 hour at room temperature (r.t.), yielding an 85% product. 3. **Product (on the right side):** - The product features a fused ring system with pyridine and indole components. - Notable groups include a benzyl-protected ether (BnO) and a carbonyl group adjacent to a methyne proton (indicated by H). This reaction involves a complex formation of heterocyclic compounds, likely through a cyclization step facilitated by the conditions outlined.

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Chapter1: Chemical Foundations
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Write the detailed mechanism

The image depicts a chemical reaction involving multiple steps:

1. **Reactants (on the left side):**
   - A pyridine ring with a pendant amine group (NH).
   - A chloroformate moiety (COCl) with a protected hydroxyl group (OBn).
   - A vinyl silane group (OTMS).

2. **Reaction Conditions:**
   - The reaction is carried out in tetrahydrofuran (THF) as the solvent.
   - The temperature is initially between -78 to 0 degrees Celsius.
   - In the second step, the mixture is stirred for 1 hour at room temperature (r.t.), yielding an 85% product.

3. **Product (on the right side):**
   - The product features a fused ring system with pyridine and indole components.
   - Notable groups include a benzyl-protected ether (BnO) and a carbonyl group adjacent to a methyne proton (indicated by H).

This reaction involves a complex formation of heterocyclic compounds, likely through a cyclization step facilitated by the conditions outlined.
Transcribed Image Text:The image depicts a chemical reaction involving multiple steps: 1. **Reactants (on the left side):** - A pyridine ring with a pendant amine group (NH). - A chloroformate moiety (COCl) with a protected hydroxyl group (OBn). - A vinyl silane group (OTMS). 2. **Reaction Conditions:** - The reaction is carried out in tetrahydrofuran (THF) as the solvent. - The temperature is initially between -78 to 0 degrees Celsius. - In the second step, the mixture is stirred for 1 hour at room temperature (r.t.), yielding an 85% product. 3. **Product (on the right side):** - The product features a fused ring system with pyridine and indole components. - Notable groups include a benzyl-protected ether (BnO) and a carbonyl group adjacent to a methyne proton (indicated by H). This reaction involves a complex formation of heterocyclic compounds, likely through a cyclization step facilitated by the conditions outlined.
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