cell anemia is inherited as an autosomal recessive trait. For the following families, hine the genotypes of the parents and offspring. When two alternative genotypes are le, list both. Two normal parents have six children, five normal and one with sickle cell anemia. A normal male and a female with sickle cell anemia have five children, all normal. A normal female and a male with sickle cell anemia have six children, three normal and three with sickle cell anemia.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Sickle cell anemia is inherited as an autosomal recessive trait. For the following families,
determine the genotypes of the parents and offspring. When two alternative genotypes are
possible, list both.
(i)
Two normal parents have six children, five normal and one with sickle cell anemia.
(ii)
A normal male and a female with sickle cell anemia have five children, all normal.
(ii)
A normal female and a male with sickle cell anemia have six children, three normal
and three with sickle cell anemia.
(iv)
Two normal parents have six children, all normal.
Construct a pedigree of the families in Ql a) (ii) and (iii). Assume that one of the
normal children in (ii) and one of the sickle cell anemia children in (iii) become the
parents of four children. Extend the pedigree to include the four children in the third
generation and predict their phenotypes.
(v)
Transcribed Image Text:Sickle cell anemia is inherited as an autosomal recessive trait. For the following families, determine the genotypes of the parents and offspring. When two alternative genotypes are possible, list both. (i) Two normal parents have six children, five normal and one with sickle cell anemia. (ii) A normal male and a female with sickle cell anemia have five children, all normal. (ii) A normal female and a male with sickle cell anemia have six children, three normal and three with sickle cell anemia. (iv) Two normal parents have six children, all normal. Construct a pedigree of the families in Ql a) (ii) and (iii). Assume that one of the normal children in (ii) and one of the sickle cell anemia children in (iii) become the parents of four children. Extend the pedigree to include the four children in the third generation and predict their phenotypes. (v)
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