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CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?

CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL Y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?
Transcribed Image Text:CASESTUDY 11 .1 Immediately following the birth of a baby girl, the attending physician requested a protein electrophoretic examination of the mother's serum. This was done on a sample that was obtained on the mother's admission to the hospital the previous day. An electrophoretic examination was also performed on the cord blood specimen. Laboratory reports are shown in Case Study Table 11.1.1. The appearance of the mother's electrophoretic pattern was within that expected for a healthy person. The electrophoretic pattern of the cord blood serum resembled the one shown in Figure 11.8C. Results for Maternal Serum Results for Cord Blood Adult Reference Interval Test Albumin 4.2 g/dL 3.5 g/dL 3.5-5.0 g/dL a,-Globulins 0.3 g/dL 0.0 g/dL 0.1-0.4 g/dL a-Globulins 1.2 g/dL 0.4 g/dL 0.3-0.8 g/dL B-Globulins 1.3 g/dL 0.7 g/dL 0.6-1.1 g/dL Y-Globulins 1.3 g/dL 1.0 g/dL 0.5-1.7 g/dL Questions 1. What protein fraction is abnormal in the cord blood serum? 2. An abnormality in this fraction is most often associated with what disease? 3. What other test(s) may be done to confirm this abnormality?
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