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Capillaries are very thin, narrow blood vessels that allow for the transfer of oxygen, carbon dioxide, and nutrients. The image shows how normal red blood cells and sickle- blood cells flow through a capillary Use information in the image to describe two ways that the sickle cell gene mutation affects the ability of red blood cells to perform their normal function Normal red blood cell section Abnormal red blood cell section

Capillaries are very thin, narrow blood vessels that allow for the transfer of oxygen, carbon dioxide, and nutrients. The image shows how normal red blood cells and sickle- blood cells flow through a capillary Use information in the image to describe two ways that the sickle cell gene mutation affects the ability of red blood cells to perform their normal function Normal red blood cell section Abnormal red blood cell section

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Sickle Cell Anemia Sickle cell anemia is a group of blood disorders that develop when a person inherits a specific recessive gene mutation. Gene mutations are permanent changes in a genetic sequence. The sickle cell mutation affects the structure of hemoglobin; hemoglobin allows red blood cells to carry oxygen. In order for a person to have sickle cell anemia, they have to inherit two copies of the recessive allele, one from each parent. The diagram shows the genotypes of an unaffected person and a person with sickle cell anemia. Normal genotype DNA GAC TGA GGA CTC CTC mRNA C||U|G| ACU CCUGAG GAG Amino acid sequence Glutamic acid Leucine Threonine Proline Sickle cell anemia genotype DNA GAC TGAGGA CAC CTC mRNA|C|U|G Amino acid sequence Glutamic acid Normal ACUCCU GUG GAG Glutamic acid Leucine Threonine Proline Valine Mutant 38 Normal red blood cells Car nofil Sickled red blood cells Capillaries are very thin, narrow blood vessels that allow for the transfer of oxygen, carbon dioxide, and nutrients. The image shows how normal red blood cells and sickle- shaped red blood cells flow through a capillary. Use information in the image to describe two ways that the sickle cell gene mutation affects the ability of red blood cells to perform their normal function. Normal red blood cell section Abnormal red blood cell section
Transcribed Image Text:Sickle Cell Anemia Sickle cell anemia is a group of blood disorders that develop when a person inherits a specific recessive gene mutation. Gene mutations are permanent changes in a genetic sequence. The sickle cell mutation affects the structure of hemoglobin; hemoglobin allows red blood cells to carry oxygen. In order for a person to have sickle cell anemia, they have to inherit two copies of the recessive allele, one from each parent. The diagram shows the genotypes of an unaffected person and a person with sickle cell anemia. Normal genotype DNA GAC TGA GGA CTC CTC mRNA C||U|G| ACU CCUGAG GAG Amino acid sequence Glutamic acid Leucine Threonine Proline Sickle cell anemia genotype DNA GAC TGAGGA CAC CTC mRNA|C|U|G Amino acid sequence Glutamic acid Normal ACUCCU GUG GAG Glutamic acid Leucine Threonine Proline Valine Mutant 38 Normal red blood cells Car nofil Sickled red blood cells Capillaries are very thin, narrow blood vessels that allow for the transfer of oxygen, carbon dioxide, and nutrients. The image shows how normal red blood cells and sickle- shaped red blood cells flow through a capillary. Use information in the image to describe two ways that the sickle cell gene mutation affects the ability of red blood cells to perform their normal function. Normal red blood cell section Abnormal red blood cell section
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