Can you do part c only i have already done a and b

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Can you do part c only i have already done a and b

2). King Tut ruled ancient Egypt from 1332 to 1323 B.C., but died as
a teenager. An analysis of STR markers carried out on samples from
the mummies of King Tut and several other mummies found in
tombs in the Valley of the Kings was published in 2010. Tut's father
was the previous Pharoah (king) Akhenaten, whose wife was Queen
Nefertiti. However, the 2010 analysis showed that Jut's mother was
Akhenaten's sister, identified in this pedigree by her mummy
number KV35YL. In answering all questions below, show key steps in
your work for full credit.
a. Calculate the inbreeding coefficient for King Tut, with annotation
of the pedigree supporting your answer.
(1/2)3+ (1/2)3 = (1/2)2 = 0.25= F
Tiye
F(aa)-gEto 2(1-F) q=0.18 F=0.25
=0.069
Akhenaten
Amenhotep III
KV35YL
Tutankhamun
b. Assume that sickle cell anemia (SCA) was relatively common in ancient Egypt as it is in Africa today. It
is caused by a recessive mutation in a single autosomal gene. If the frequency of the SCA allele in the
general population to which Tut belonged was 0.18, what is the probability that King Tut would have
had sickle cell anemia?
c. Assuming random mating in the general population of Egypt at that time and the SCA allele frequency
of 0.18, what was the frequency of... (i) SCA homozygotes (have disease):
(ii) SCA carriers:
(iii) SCA non-carriers:
Transcribed Image Text:2). King Tut ruled ancient Egypt from 1332 to 1323 B.C., but died as a teenager. An analysis of STR markers carried out on samples from the mummies of King Tut and several other mummies found in tombs in the Valley of the Kings was published in 2010. Tut's father was the previous Pharoah (king) Akhenaten, whose wife was Queen Nefertiti. However, the 2010 analysis showed that Jut's mother was Akhenaten's sister, identified in this pedigree by her mummy number KV35YL. In answering all questions below, show key steps in your work for full credit. a. Calculate the inbreeding coefficient for King Tut, with annotation of the pedigree supporting your answer. (1/2)3+ (1/2)3 = (1/2)2 = 0.25= F Tiye F(aa)-gEto 2(1-F) q=0.18 F=0.25 =0.069 Akhenaten Amenhotep III KV35YL Tutankhamun b. Assume that sickle cell anemia (SCA) was relatively common in ancient Egypt as it is in Africa today. It is caused by a recessive mutation in a single autosomal gene. If the frequency of the SCA allele in the general population to which Tut belonged was 0.18, what is the probability that King Tut would have had sickle cell anemia? c. Assuming random mating in the general population of Egypt at that time and the SCA allele frequency of 0.18, what was the frequency of... (i) SCA homozygotes (have disease): (ii) SCA carriers: (iii) SCA non-carriers:
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