Can someone help me identify if these structures have R or S configurations?

Chemistry: Principles and Practice
3rd Edition
ISBN:9780534420123
Author:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Chapter10: Molecular Structure And Bonding Theories
Section: Chapter Questions
Problem 10.127QE
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Can someone help me identify if these structures have R or S configurations? 

**Title: Assigning Absolute Configuration of Chirality Centers**

**Objective:**  
Identify the absolute configuration of the chirality centers in each of the following compounds as R or S. If multiple chirality centers are present, indicate the stereochemical designations as: RR, SS, RS, or SR.

*Note: Other terms used for chirality center include chiral center, stereocenter, and stereogenic center.*

### Compounds:

1. **First Compound:**

   **Structure:**
   - The molecule contains a cyclopropane ring.
   - Two chlorine (Cl) atoms are attached to the cyclopropane, one with a wedge (indicating it is pointing out of the plane towards the viewer) and the other with a dashed line (indicating it is pointing behind the plane).
   
   **Task:**
   - Determine the absolute configuration (R or S) for the chiral center with two chlorine atoms.

2. **Second Compound:**

   **Structure:**
   - The molecule is a linear carbon chain with an OH group and a methyl (CH₃) group.
   - The OH group is represented with a wedge, while the hydrogen atom (H) is represented with a dashed line, both attached to the same carbon.
   
   **Task:**
   - Determine the absolute configuration (R or S) for the chiral center with the hydroxyl group and methyl group.

3. **Third Compound:**

   **Structure:**
   - The molecule is a cyclohexane ring with two substituents: a methyl group and a hydroxyl group.
   - The OH group is represented with a wedge. 

   **Task:**
   - Determine the absolute configuration (R or S) for the chiral center with the hydroxyl group.

### Conclusion

Each compound requires analysis of the spatial arrangement of groups around the chiral centers, following the Cahn-Ingold-Prelog priority rules to assign the R or S configuration appropriately. Once configurations are identified, combinations like RR, SS, RS, or SR can be determined for compounds with multiple chiral centers.
Transcribed Image Text:**Title: Assigning Absolute Configuration of Chirality Centers** **Objective:** Identify the absolute configuration of the chirality centers in each of the following compounds as R or S. If multiple chirality centers are present, indicate the stereochemical designations as: RR, SS, RS, or SR. *Note: Other terms used for chirality center include chiral center, stereocenter, and stereogenic center.* ### Compounds: 1. **First Compound:** **Structure:** - The molecule contains a cyclopropane ring. - Two chlorine (Cl) atoms are attached to the cyclopropane, one with a wedge (indicating it is pointing out of the plane towards the viewer) and the other with a dashed line (indicating it is pointing behind the plane). **Task:** - Determine the absolute configuration (R or S) for the chiral center with two chlorine atoms. 2. **Second Compound:** **Structure:** - The molecule is a linear carbon chain with an OH group and a methyl (CH₃) group. - The OH group is represented with a wedge, while the hydrogen atom (H) is represented with a dashed line, both attached to the same carbon. **Task:** - Determine the absolute configuration (R or S) for the chiral center with the hydroxyl group and methyl group. 3. **Third Compound:** **Structure:** - The molecule is a cyclohexane ring with two substituents: a methyl group and a hydroxyl group. - The OH group is represented with a wedge. **Task:** - Determine the absolute configuration (R or S) for the chiral center with the hydroxyl group. ### Conclusion Each compound requires analysis of the spatial arrangement of groups around the chiral centers, following the Cahn-Ingold-Prelog priority rules to assign the R or S configuration appropriately. Once configurations are identified, combinations like RR, SS, RS, or SR can be determined for compounds with multiple chiral centers.
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