Calculate the fractional saturation for myoglobin when pO2 is 5 torr. The myoglobin p50 is 2.8 torr. 0.28 0.36 0.56 0.64

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Calculate the fractional saturation
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**Problem Statement:**
Calculate the fractional saturation for myoglobin when pO₂ is 5 torr. The myoglobin P₅₀ is 2.8 torr.

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**Multiple Choice Answers:**

- ○ 0.28
- ○ 0.36
- ○ 0.56
- ○ 0.64

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**Explanation:**
To solve this problem, use the fractional saturation formula for myoglobin:

\[ Y = \frac{pO_2}{pO_2 + P_{50}} \]

where:
- \( Y \) is the fractional saturation.
- \( pO_2 \) is the partial pressure of oxygen.
- \( P_{50} \) is the partial pressure at which myoglobin is 50% saturated.

Given:
- \( pO_2 = 5 \) torr
- \( P_{50} = 2.8 \) torr

Substitute the values into the formula:

\[ Y = \frac{5}{5 + 2.8} = \frac{5}{7.8} \approx 0.64 \]

So, the correct answer is:

- ○ 0.64

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**Interpretation of Results:**
The fractional saturation of myoglobin at a partial pressure of oxygen (pO₂) of 5 torr is approximately 0.64. This means that 64% of the myoglobin molecules are saturated with oxygen at this partial pressure.

This type of problem helps in understanding how gases like oxygen bind to proteins such as myoglobin, which is crucial in fields like physiology and biochemistry.

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Transcribed Image Text:--- **Problem Statement:** Calculate the fractional saturation for myoglobin when pO₂ is 5 torr. The myoglobin P₅₀ is 2.8 torr. --- **Multiple Choice Answers:** - ○ 0.28 - ○ 0.36 - ○ 0.56 - ○ 0.64 --- **Explanation:** To solve this problem, use the fractional saturation formula for myoglobin: \[ Y = \frac{pO_2}{pO_2 + P_{50}} \] where: - \( Y \) is the fractional saturation. - \( pO_2 \) is the partial pressure of oxygen. - \( P_{50} \) is the partial pressure at which myoglobin is 50% saturated. Given: - \( pO_2 = 5 \) torr - \( P_{50} = 2.8 \) torr Substitute the values into the formula: \[ Y = \frac{5}{5 + 2.8} = \frac{5}{7.8} \approx 0.64 \] So, the correct answer is: - ○ 0.64 --- **Interpretation of Results:** The fractional saturation of myoglobin at a partial pressure of oxygen (pO₂) of 5 torr is approximately 0.64. This means that 64% of the myoglobin molecules are saturated with oxygen at this partial pressure. This type of problem helps in understanding how gases like oxygen bind to proteins such as myoglobin, which is crucial in fields like physiology and biochemistry. ---
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