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c. i. Identify a field of research, other than dyskeratosis congenita, that could use knowledge gained about telomerase and telomeres. Explain how this information might be used. c. ii. Evaluate how this research could affect either an individual or society. Include one potential advantage and one potential disadvantage in your evaluatior

c. i. Identify a field of research, other than dyskeratosis congenita, that could use knowledge gained about telomerase and telomeres. Explain how this information might be used. c. ii. Evaluate how this research could affect either an individual or society. Include one potential advantage and one potential disadvantage in your evaluatior

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Use the following additional information to answer the next two parts of the question. Knowledge that researchers have gained about telomerase through their study of dyskeratosis congenita could be of use to researchers in other fields of study. c. i. Identify a field of research, other than dyskeratosis congenita, that could use knowledge gained about telomerase and telomeres. Explain how this information might be used. c. ii. Evaluate how this research could affect either an individual or society. Include one potential advantage and one potential disadvantage in your evaluatior
Transcribed Image Text:Use the following additional information to answer the next two parts of the question. Knowledge that researchers have gained about telomerase through their study of dyskeratosis congenita could be of use to researchers in other fields of study. c. i. Identify a field of research, other than dyskeratosis congenita, that could use knowledge gained about telomerase and telomeres. Explain how this information might be used. c. ii. Evaluate how this research could affect either an individual or society. Include one potential advantage and one potential disadvantage in your evaluatior
From the time that a sperm cell first fertilizes an egg cell, a "biological clock" begins ticking within the zygote. The number of times that cells, all of which come from the original zygote, will be able to divide is limited. On each end of a chromosome is a structure known as a telomere. Each time the DNA replicates, teh telmere shortens. This progressive shortening will eventually cause the telomere length to shorten to the point that the DNA will no longer be able to replicate, causing the cell to die. An enzyme known as telomerase is found in rapidly dividing cells, such as those in the testes, skin, hair, and bone marrow. Telomerase lengthens telomeres so that a cell can continue to divide. Dyskeratosis congenita is an inherited human disorder in which patients have reduced telomerase activity. Affected individuals die between the ages of 16 and 50 years. Death is usually associated with bone marrow failure, although the patient will exhibit many other symptoms. Kyskeratosis congenita is caused by- la mutation in either the X chromosome or an autosome. In the sex-linked disorder, affected individuals have low levels of telomerase and they have shoerter-than-normal telomeres in various cells. In the autosomal disorder, affected individuals can be heterozygous. In some autosomal patients, a segment of 821 base pairs of the telomerase gene has been deleted. In other patients, one or two nitrogen base pair substitutions have occurred.
Transcribed Image Text:From the time that a sperm cell first fertilizes an egg cell, a "biological clock" begins ticking within the zygote. The number of times that cells, all of which come from the original zygote, will be able to divide is limited. On each end of a chromosome is a structure known as a telomere. Each time the DNA replicates, teh telmere shortens. This progressive shortening will eventually cause the telomere length to shorten to the point that the DNA will no longer be able to replicate, causing the cell to die. An enzyme known as telomerase is found in rapidly dividing cells, such as those in the testes, skin, hair, and bone marrow. Telomerase lengthens telomeres so that a cell can continue to divide. Dyskeratosis congenita is an inherited human disorder in which patients have reduced telomerase activity. Affected individuals die between the ages of 16 and 50 years. Death is usually associated with bone marrow failure, although the patient will exhibit many other symptoms. Kyskeratosis congenita is caused by- la mutation in either the X chromosome or an autosome. In the sex-linked disorder, affected individuals have low levels of telomerase and they have shoerter-than-normal telomeres in various cells. In the autosomal disorder, affected individuals can be heterozygous. In some autosomal patients, a segment of 821 base pairs of the telomerase gene has been deleted. In other patients, one or two nitrogen base pair substitutions have occurred.
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