c) The signal recognition particle (SRP) plays an important role in bringing proteins to the ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER localization pathway. Please list at least two essential binding partners of the SRP.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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This has 3 parts, please answer and explain in depth
a)
You are studying ER localization in mammalian cells. You notice that when a mutation
is introduced to protein A, there are no proteins in the ER at all. What is a reasonable identity of
protein A?
b)
Alternatively, when a mutation is introduced to protein B, only one protein that was
supposed to be in the ER is now in the cytoplasm. please suggest a specific type of sequence
within protein B in which this mutation might have occurred.
Transcribed Image Text:a) You are studying ER localization in mammalian cells. You notice that when a mutation is introduced to protein A, there are no proteins in the ER at all. What is a reasonable identity of protein A? b) Alternatively, when a mutation is introduced to protein B, only one protein that was supposed to be in the ER is now in the cytoplasm. please suggest a specific type of sequence within protein B in which this mutation might have occurred.
c) The signal recognition particle (SRP) plays an important role in bringing proteins to the
ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER
localization pathway. Please list at least two essential binding partners of the SRP.
Transcribed Image Text:c) The signal recognition particle (SRP) plays an important role in bringing proteins to the ER. There are multiple regions in the SRP that can bind to different proteins involved in the ER localization pathway. Please list at least two essential binding partners of the SRP.
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