Bromoetherification, the addition of the elements of Br and OR to a double bond, is a common method for constructing rings containing oxygen atoms. This reaction has been used in the synthesis of the polyether antibiotic monensin (Problem 21.36). Draw a stepwise mechanism for the following intramolecular bromoetherification reaction. Br Br2 + HBr

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Bromoetherification, the addition of the elements of Br and OR to a double bond, is a common method for constructing rings
containing oxygen atoms. This reaction has been used in the synthesis of the polyether antibiotic monensin (Problem 21.36).
Draw a stepwise mechanism for the following intramolecular bromoetherification reaction.
Br
Br2
+
HBr
Transcribed Image Text:Bromoetherification, the addition of the elements of Br and OR to a double bond, is a common method for constructing rings containing oxygen atoms. This reaction has been used in the synthesis of the polyether antibiotic monensin (Problem 21.36). Draw a stepwise mechanism for the following intramolecular bromoetherification reaction. Br Br2 + HBr
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