Br -60% Br Br CH3OH NaN3 DMF

Chemistry
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Chapter1: Chemical Foundations
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Complete the following reactions: indicate the mechanism (SN1 or SN2). If the reaction does not proceed, indicate so and the reason as to why it would not. 

### Chemical Reactions Involving Haloalkanes

This educational segment focuses on reactions involving brominated aromatic compounds in the presence of solvents and reagents.

#### Reaction 1:
- **Starting Material**: 
  - 1,4-Dibromo-2-methylbenzene (also known as para-dibromo-toluene).
  
- **Solvent**: 
  - Methanol (CH₃OH).
  
- **Reaction Details**:
  - The reaction is indicated by an arrow pointing from the brominated aromatic compound to the solvent.
  - This setup suggests a transformation or a nucleophilic substitution reaction. Methanol can act as a nucleophile, potentially leading to the substitution of a bromine atom by a methoxy group (-OCH₃).

#### Reaction 2:
- **Starting Material**:
  - 1,4-Dibromo-2-methylbenzene (same as in Reaction 1).
  
- **Reagent**:
  - Sodium azide (NaN₃).
  
- **Solvent**:
  - Dimethylformamide (DMF).
  
- **Reaction Details**:
  - The chemical equation shows an arrow from the starting brominated compound to the mixture of NaN₃ and DMF.
  - Sodium azide acts as a nucleophile in this reaction. The presence of DMF as a polar aprotic solvent facilitates the nucleophilic substitution, potentially replacing a bromine atom with an azide group (N₃).

### Graphical Summary:
- The diagram presents two distinct chemical reactions that demonstrate the versatility of haloarene compounds with different nucleophiles and solvents.
- In both reactions, the methyl group remains unchanged, focusing primarily on the substitution of bromine atoms.

This illustrates typical strategies in organic synthesis involving nucleophilic aromatic substitution (S_NAr) reactions.
Transcribed Image Text:### Chemical Reactions Involving Haloalkanes This educational segment focuses on reactions involving brominated aromatic compounds in the presence of solvents and reagents. #### Reaction 1: - **Starting Material**: - 1,4-Dibromo-2-methylbenzene (also known as para-dibromo-toluene). - **Solvent**: - Methanol (CH₃OH). - **Reaction Details**: - The reaction is indicated by an arrow pointing from the brominated aromatic compound to the solvent. - This setup suggests a transformation or a nucleophilic substitution reaction. Methanol can act as a nucleophile, potentially leading to the substitution of a bromine atom by a methoxy group (-OCH₃). #### Reaction 2: - **Starting Material**: - 1,4-Dibromo-2-methylbenzene (same as in Reaction 1). - **Reagent**: - Sodium azide (NaN₃). - **Solvent**: - Dimethylformamide (DMF). - **Reaction Details**: - The chemical equation shows an arrow from the starting brominated compound to the mixture of NaN₃ and DMF. - Sodium azide acts as a nucleophile in this reaction. The presence of DMF as a polar aprotic solvent facilitates the nucleophilic substitution, potentially replacing a bromine atom with an azide group (N₃). ### Graphical Summary: - The diagram presents two distinct chemical reactions that demonstrate the versatility of haloarene compounds with different nucleophiles and solvents. - In both reactions, the methyl group remains unchanged, focusing primarily on the substitution of bromine atoms. This illustrates typical strategies in organic synthesis involving nucleophilic aromatic substitution (S_NAr) reactions.
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