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Br 3. HCI, H2O

Br 3. HCI, H2O

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Predict the product of the following reaction sequence:

### Reaction Scheme for Synthesis of Carboxylic Acid This image represents a three-step synthesis process commonly used in organic chemistry to convert an alkyl bromide to a carboxylic acid. 1. **Starting Material:** - The compound on the left is an alkyl bromide, specifically 2-bromopropane. 2. **Reaction Steps:** - **Step 1:** Reaction with Magnesium (Mg) - The first step involves treating the alkyl bromide with magnesium to form a Grignard reagent. The magnesium inserts into the carbon-bromine bond to create an organomagnesium compound. - **Step 2:** Reaction with Carbon Dioxide (CO₂) - The Grignard reagent is then reacted with carbon dioxide. This step is crucial for the insertion of a carbonyl group, forming a carboxylate salt intermediate. - **Step 3:** Acid Work-Up with Hydrochloric Acid and Water (HCl, H₂O) - Finally, the carboxylate salt is acidified using hydrochloric acid and water, resulting in the formation of the corresponding carboxylic acid. This sequence illustrates a typical transformation in organic synthesis, enabling the conversion of simple alkyl halides into more complex carboxylic acids with potential applications in various chemical industries.
Transcribed Image Text:### Reaction Scheme for Synthesis of Carboxylic Acid This image represents a three-step synthesis process commonly used in organic chemistry to convert an alkyl bromide to a carboxylic acid. 1. **Starting Material:** - The compound on the left is an alkyl bromide, specifically 2-bromopropane. 2. **Reaction Steps:** - **Step 1:** Reaction with Magnesium (Mg) - The first step involves treating the alkyl bromide with magnesium to form a Grignard reagent. The magnesium inserts into the carbon-bromine bond to create an organomagnesium compound. - **Step 2:** Reaction with Carbon Dioxide (CO₂) - The Grignard reagent is then reacted with carbon dioxide. This step is crucial for the insertion of a carbonyl group, forming a carboxylate salt intermediate. - **Step 3:** Acid Work-Up with Hydrochloric Acid and Water (HCl, H₂O) - Finally, the carboxylate salt is acidified using hydrochloric acid and water, resulting in the formation of the corresponding carboxylic acid. This sequence illustrates a typical transformation in organic synthesis, enabling the conversion of simple alkyl halides into more complex carboxylic acids with potential applications in various chemical industries.
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