Black Forest Biologicals, a biotech startup, has a promising Alzheimer's drug candidate Compound SLT-88 entering Phase I trials this year. SLT-88 is the only product formed by the reaction of two precursor compounds A and B, both of which are quite expensive. The chief medicinal chemist of Black Forest is trying out different reaction conditions to minimize the cost of manufacturing SLT-88. In the table below are listed the initial and final amounts of A and B used under two different trial conditions, and also the actual amount of SLT-88 recovered in each case. Complete the table by calculating the theoretical yield of SLT-88 and the percent yield of SLT-88. Round your amounts to the nearest milligram and your percentages to the nearest whole percent. amount of A amount of B yield of SLT-88 0 H Trial initial final initial final theoretical actual 1 550. mg 0 mg 400. mg 256. mg 0 423. mg 350. mg 0 mg 550. mg 352. mg 0 471, mg 2 % % Sº 00 0.0 X S ? 8全图 do
Black Forest Biologicals, a biotech startup, has a promising Alzheimer's drug candidate Compound SLT-88 entering Phase I trials this year. SLT-88 is the only product formed by the reaction of two precursor compounds A and B, both of which are quite expensive. The chief medicinal chemist of Black Forest is trying out different reaction conditions to minimize the cost of manufacturing SLT-88. In the table below are listed the initial and final amounts of A and B used under two different trial conditions, and also the actual amount of SLT-88 recovered in each case. Complete the table by calculating the theoretical yield of SLT-88 and the percent yield of SLT-88. Round your amounts to the nearest milligram and your percentages to the nearest whole percent. amount of A amount of B yield of SLT-88 0 H Trial initial final initial final theoretical actual 1 550. mg 0 mg 400. mg 256. mg 0 423. mg 350. mg 0 mg 550. mg 352. mg 0 471, mg 2 % % Sº 00 0.0 X S ? 8全图 do
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![**Black Forest Biologicals: Alzheimer's Drug Candidate Compound SLT-88 Trials**
Black Forest Biologicals, a biotech startup, has developed a promising Alzheimer's drug candidate known as Compound SLT-88, which is about to enter Phase I trials this year. SLT-88 is produced through a reaction involving two precursor compounds, A and B, both of which are quite expensive. The chief medicinal chemist at Black Forest is experimenting with different reaction conditions to minimize the cost of manufacturing SLT-88.
**Objective:**
To determine the initial and final amounts of compounds A and B used under two different trial conditions, and to calculate the theoretical and actual yield of SLT-88. Additionally, to compute the percent yield of SLT-88 for each trial.
**Data:**
*The table below provides the initial and final amounts of compounds A and B, along with the actual amount of SLT-88 recovered in each case.*
| Trial | Amount of A (mg) | Amount of B (mg) | Yield of SLT-88 |
|-------|-------------------------|-------------------------|---------------------|
| | Initial | Final | Initial | Final | Theoretical | Actual | Percentage (%) |
| 1 | 550 | 0 | 400 | 256 | | 423 | |
| 2 | 350 | 0 | 550 | 352 | | 471 | |
**Instructions to Complete the Table:**
1. *Calculate the Theoretical Yield of SLT-88:* The theoretical yield can be determined using stoichiometry based on the initial amounts of precursors A and B, assuming complete conversion to SLT-88.
2. *Calculate the Percent Yield:*
- Percent yield is given by the formula:
\[
\text{Percent Yield} = \left( \frac{\text{Actual Yield}}{\text{Theoretical Yield}} \right) \times 100
\]
- Round your percentages to the nearest whole percent.
The trial data allows for a better understanding of the efficiency of the reaction under different conditions and helps in optimizing the reaction for cost-effective production of SLT-88. This approach is essential for advancing from lab-scale synthesis to industrial-scale production, ensuring that the process is economically viable.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F7c14a699-de9b-4c1d-9356-4bb35f1041ad%2Fe47d5600-3c29-4ff0-97d5-fb9c29cd84c5%2Fuvvjssm_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Black Forest Biologicals: Alzheimer's Drug Candidate Compound SLT-88 Trials**
Black Forest Biologicals, a biotech startup, has developed a promising Alzheimer's drug candidate known as Compound SLT-88, which is about to enter Phase I trials this year. SLT-88 is produced through a reaction involving two precursor compounds, A and B, both of which are quite expensive. The chief medicinal chemist at Black Forest is experimenting with different reaction conditions to minimize the cost of manufacturing SLT-88.
**Objective:**
To determine the initial and final amounts of compounds A and B used under two different trial conditions, and to calculate the theoretical and actual yield of SLT-88. Additionally, to compute the percent yield of SLT-88 for each trial.
**Data:**
*The table below provides the initial and final amounts of compounds A and B, along with the actual amount of SLT-88 recovered in each case.*
| Trial | Amount of A (mg) | Amount of B (mg) | Yield of SLT-88 |
|-------|-------------------------|-------------------------|---------------------|
| | Initial | Final | Initial | Final | Theoretical | Actual | Percentage (%) |
| 1 | 550 | 0 | 400 | 256 | | 423 | |
| 2 | 350 | 0 | 550 | 352 | | 471 | |
**Instructions to Complete the Table:**
1. *Calculate the Theoretical Yield of SLT-88:* The theoretical yield can be determined using stoichiometry based on the initial amounts of precursors A and B, assuming complete conversion to SLT-88.
2. *Calculate the Percent Yield:*
- Percent yield is given by the formula:
\[
\text{Percent Yield} = \left( \frac{\text{Actual Yield}}{\text{Theoretical Yield}} \right) \times 100
\]
- Round your percentages to the nearest whole percent.
The trial data allows for a better understanding of the efficiency of the reaction under different conditions and helps in optimizing the reaction for cost-effective production of SLT-88. This approach is essential for advancing from lab-scale synthesis to industrial-scale production, ensuring that the process is economically viable.
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