A mutation in a bacterial protein-coding gene with a standard consensus promoter deletes the two base pairs at the transcription start site and at the position immediately preceding it (the -1 and +1 positions). What will be the most likely effects, if any, on the transcript and the encoded polypeptide? Both the transcript and the polypeptide will be unchanged. O The transcript will be 2 bases shorter; the polypeptide will be completely different due to a frameshift. The transcript will be 2 bases shorter; the polypeptide will be one amino acid shorter but otherwise unchanged. Transcription will not be initiated, so ncither a transcript nor a polypeptide will be produced. O The transcript will be 2 bases shorter: the polypcptide will be unchanged.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A mutation in a bacterial protein-coding gene with a standard consensus promoter deletes the two base
pairs at the transcription start site and at the position immediately preceding it (the -1 and +1 positions).
What will be the most likely effects, if any, on the transcript and the encoded polypeptide?
Both the transcript and the polypeptide will be unchanged.
O The transcript will be 2 bases shorter; the polypeptide will be completely different due to a
frameshift.
The transcript will be 2 bases shorter; the polypeptide will be one amino acid shorter but otherwise
unchanged.
Transcription will not be initiated, so ncither a transcript nor a polypeptide will be produced.
O The transcript will be 2 bases shorter: the polypcptide will be unchanged.
Transcribed Image Text:A mutation in a bacterial protein-coding gene with a standard consensus promoter deletes the two base pairs at the transcription start site and at the position immediately preceding it (the -1 and +1 positions). What will be the most likely effects, if any, on the transcript and the encoded polypeptide? Both the transcript and the polypeptide will be unchanged. O The transcript will be 2 bases shorter; the polypeptide will be completely different due to a frameshift. The transcript will be 2 bases shorter; the polypeptide will be one amino acid shorter but otherwise unchanged. Transcription will not be initiated, so ncither a transcript nor a polypeptide will be produced. O The transcript will be 2 bases shorter: the polypcptide will be unchanged.
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