Benzocaine has been tested as an anaesthetic for inhibition of m1 muscarinic acetylcholine signalling. Using the data below, plot a graph and determine the IC50. Concentration (M) 1 x 10-6 10 x 10-6 100 x 10-6 1000 x 10-6 10000 x 10-6 100000 x 10-6 % of control response 97 93 78 56 42 36

Benzocaine has been tested as an anaesthetic for inhibition of m1 muscarinic acetylcholine signalling. Using the data below, plot a graph and determine the IC50. Concentration (M) 1 x 10-6 10 x 10-6 100 x 10-6 1000 x 10-6 10000 x 10-6 100000 x 10-6 % of control response 97 93 78 56 42 36

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Spectroanalytical Methods

Spectroanalytical methods measure the wavelength and intensity of radiations that are either emitted or absorbed by a molecular or atomic species. These methods are useful for evaluating the electronic or atomic arrangement of the molecules of a given analyte.

Question

Benzocaine has been tested as an anaesthetic for inhibition of m1 muscarinic
acetylcholine signalling. Using the data below, plot a graph and determine the
IC50.
Concentration (M)
1 x 10-6
10 x 10-6
100 x 10-6
1000 x 10-6
10000 x 10-6
100000 x 10-6
% of control response
97
93
78
56
42
36

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