Below you will see a wedge-dash diagram, and an incomplete Newman projection with the designated bond you are looking down. Your task is to complete the Newman projection, by filling-in each box below, with the substituents (e.g. CH3, Br, H, etc. - whichever substituents remain in the molecule) that would give the MOST STABLE conformer. CH₂ 1: 2: 3: 4: CH₂ 1 H₂C CH(CH₂)₂ 2 3 Looking down C4-C3 bond 4
Below you will see a wedge-dash diagram, and an incomplete Newman projection with the designated bond you are looking down. Your task is to complete the Newman projection, by filling-in each box below, with the substituents (e.g. CH3, Br, H, etc. - whichever substituents remain in the molecule) that would give the MOST STABLE conformer. CH₂ 1: 2: 3: 4: CH₂ 1 H₂C CH(CH₂)₂ 2 3 Looking down C4-C3 bond 4
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:## Stereochemistry
### Determine the Stereochemistry Configuration
Consider the molecule given below. Assign the R or S configuration for each of the chiral centers.
#### Molecules and Diagram Description:
**Molecule 1**:
```
CH3
|
H3C--C--CH2OH
|
H
```
**Molecule 2**:
```
CH3
|
HO--C--CH3
|
H
```
**Instructions**:
Using the wedge-and-dash diagram of the molecule, fill in the boxes for the most stable conformer. Provide the configuration for the highlighted chiral centers by looking down the C4-C3 axis and filling in with the substituents like H, CH₃, OH, etc.
**Boxes**:
```
4: ________
3: ________
2: ________
1: ________
```
The graphical diagram illustrates two molecules with chiral centers. The visualization emphasizes the need to determine the R/S configuration of each stereogenic center by analyzing the substituents connected to them.
---
#### Explanation:
- To assign an R or S configuration to a chiral center:
1. Identify the four different substituents attached to the chiral carbon.
2. Assign priorities (1 to 4) based on atomic numbers, with 1 being the highest priority.
3. Orient the molecule so that the lowest priority group (4) is pointing away from you.
4. Observe the sequence from 1 to 3. If it goes clockwise, the configuration is R. If counterclockwise, it is S.
---
Complete this exercise by analyzing each molecule's chiral centers and noting the R/S configuration in the boxes provided.
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