Below picture depicts the enzymatic reaction where carboxylesterase mediated hydrolysis reaction of à hypothetical carboxyl-ester, water molecule is needed for this reaction step in order to liberate acid metabolite.
Below picture depicts the enzymatic reaction where carboxylesterase mediated hydrolysis reaction of à hypothetical carboxyl-ester, water molecule is needed for this reaction step in order to liberate acid metabolite.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Below picture depicts the enzymatic reaction where carboxylesterase mediated
hydrolysis reaction of à hypothetical carboxyl-ester, water molecule is needed
for this reaction step in order to liberate acid metabolite.
a. What is the interaction taking place between Glutamate and Histidine?
b. If serine is replaced by alanine how the reaction occurs
C. If Glutamate is replaced by arginine what happens to the reaction?
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