Below is the elimination reaction of 4-fluoro-4-(4-nitrophenyl)butan-2-one forming 4-(4-nitrophenyl)but-3-en-2-one.baseF-O2NO,NTwo sets of experiments were carried out with different reactants as shown below. The k /kpvalues are also given below.(L is either Hydrogen, H OR Deuterium, D)Set 1O,NkH/kp = 3.7Set 2O,NkH/kp= 1.5a) Even though Sets 1 and 2 show two different kinetic isotope effect values, bothreactions took place via the SAME mechanism.Propose ONE mechanism that would explain both observations in Sets 1 and 2. Explainyour answer.b) Suggest another modification on the experiment to further support your above proposal

a. The given reaction follows E1CB pathway. F is a bad leaving group. Hence, base will abstract the…

Below is the elimination reaction of 4-fluoro-4-(4-nitrophenyl)butan-2-one forming 4-(4- nitrophenyl)but-3-en-2-one. ore F base F- O,N O2N' Two sets of experiments were carried out with different reactants as shown below. The k#/kp values are also given below. (L is either Hydrogen, H OR Deuterium, D) Set 1 k#/kp = 3.7 Set 2 kµ/kp = 1.5 a) Even though Sets 1 and 2 show two different kinetic isotope effect values, both reactions took place via the SAME mechanism. Propose ONE mechanism that would explain both observations in Sets 1 and 2. Explai your answer.

Below is the elimination reaction of 4-fluoro-4-(4-nitrophenyl)butan-2-one forming 4-(4- nitrophenyl)but-3-en-2-one. ore F base F- O,N O2N' Two sets of experiments were carried out with different reactants as shown below. The k#/kp values are also given below. (L is either Hydrogen, H OR Deuterium, D) Set 1 k#/kp = 3.7 Set 2 kµ/kp = 1.5 a) Even though Sets 1 and 2 show two different kinetic isotope effect values, both reactions took place via the SAME mechanism. Propose ONE mechanism that would explain both observations in Sets 1 and 2. Explai your answer.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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