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Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. I Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.

Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. I Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. | Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.
Transcribed Image Text:Below is a list of mutations commonly found in different components of the hormone-signaling pathways. | Mutant #1: The icRH undergoes a loss-of- function mutation. | Mutant #2: GSK-3B can no longer be phosphorylated. | Mutant #3: ERK is constitutively active. | Mutant #4: Lyn undergoes a gain-of function mutation. | Mutant #5: The cyclin A gene's DNA is highly compacted and inaccessible. la. Mutations in the signalling pathways depicted above have been associated with an increased incidence of several types of cancer. Which of the above mutations (#1-5) could potentially cause cancer in an individual? Be sure to explain why.
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