Below are protein sequences for a Kinesin II motor protein from Chlamydomonas reinhardtii and from Homo sapiens. Chlamydomonas reinhardti Kinesin II Motor Protein MASGGECVKVAVRCRPLNGKEKGDNRATIVEVDNKTGOVTLNNPKGDEPPKTFTFDNAFD WNVTQRDVYDVARPIVNSVMDGYNGTIFAYGOTGTGKTHTMEGFPTPELOGIIPNCFDH VFETVNSSTGKQWMVRASYLEIYNEEVRDLLSKDPKNKLELKEHKDSGVYVKGLNAFVVK GVPELKNVLEVGKKNRSVGATLMNQDSSRSHSIFTITIETIEOTQAQPEGHIRVGKLNLV DLAGSERQSKTGATGORLKEATKINLSLSALGNVISALVDGKSGHVPYRDSKLTRLLQDS LGGNTKTIMCANMGPADWNYDETLSTLRYANRAKNIKNKPKINEDPKDAMLREFQDEIAR LKAALEAEGGALPEGFATGPGGEIIVEKVVQVPKALDASFLEGMRKDMEEQMKKELASQQ AAALNDEQLOKVKEEAAAKAKAEAARLEEEKKKAEEEAARMORKQQKIKAEMDKKSLDAE QIRAEKEALAKKLKAMESKILKGDQAGGLAEVTKKKEEELKRKEQELERRRKEEEEQRKK IQVMEEQQLAMEDKYKDKADEADOKTKKLKKLWKKFQEVNAEVEDMYKEFQREKEDLLES IRMLQDQMQLKDMVIEAFIPPEEVQKVMKRAHWDDEREVWVLERLSDIGKRETAQGASRR PVSASGORRPTSDFAKLANAMGDMNPRFKSENILNLELDLPERTTYDYEGPGVDPRVOAA FDCVS Homo sapiens KIFIC Motor Protein MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF DAVYDASSKQADLYDETVRPLIDSVLOGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI PNAFEHIFTHISRSONQOYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL SSFVTKNVKEIEHVMNLGNOTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL GNVIAALAGNRSTHIPYRDSKLTRLLODSLGGNAKTIMVATLGPASHSYDESLSTURFAN RAKNIKNKPRVNEDPKDTLLREFQEE ARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLOEQKERLEEEKAAIQDDRS LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE LKROEIAEOKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIENFIPPEEKNKIM NRL FLDCEEEQWK FQPLVPAGVSQMKKRPTSAVGYKRPISOYARVAMAMGSHPRYRAENIMFLELDVSPPAVE EMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPORPPPSTTHASLASA SLRPATVADHE Align these sequences using NCBI Protein Protein BLAST as you did in problem set 5 and answer the following three questions: al What is the percent identity between these Chlamydomonas and Human Kinesin Il proteins? B) For the proteins that you aligned in the previous question, find the longest contiguous stretch of identical amino acids. What is the sequence of these identical amino acids? c) If you aligned the cDNA sequences for the Chlamydomonas and Human proteins that you aligned above, do you predict that the percent identity would be higher or lower than the percent identity for the alignment of the polypeptide sequences? Explain your answer.
Below are protein sequences for a Kinesin II motor protein from Chlamydomonas reinhardtii and from Homo sapiens. Chlamydomonas reinhardti Kinesin II Motor Protein MASGGECVKVAVRCRPLNGKEKGDNRATIVEVDNKTGOVTLNNPKGDEPPKTFTFDNAFD WNVTQRDVYDVARPIVNSVMDGYNGTIFAYGOTGTGKTHTMEGFPTPELOGIIPNCFDH VFETVNSSTGKQWMVRASYLEIYNEEVRDLLSKDPKNKLELKEHKDSGVYVKGLNAFVVK GVPELKNVLEVGKKNRSVGATLMNQDSSRSHSIFTITIETIEOTQAQPEGHIRVGKLNLV DLAGSERQSKTGATGORLKEATKINLSLSALGNVISALVDGKSGHVPYRDSKLTRLLQDS LGGNTKTIMCANMGPADWNYDETLSTLRYANRAKNIKNKPKINEDPKDAMLREFQDEIAR LKAALEAEGGALPEGFATGPGGEIIVEKVVQVPKALDASFLEGMRKDMEEQMKKELASQQ AAALNDEQLOKVKEEAAAKAKAEAARLEEEKKKAEEEAARMORKQQKIKAEMDKKSLDAE QIRAEKEALAKKLKAMESKILKGDQAGGLAEVTKKKEEELKRKEQELERRRKEEEEQRKK IQVMEEQQLAMEDKYKDKADEADOKTKKLKKLWKKFQEVNAEVEDMYKEFQREKEDLLES IRMLQDQMQLKDMVIEAFIPPEEVQKVMKRAHWDDEREVWVLERLSDIGKRETAQGASRR PVSASGORRPTSDFAKLANAMGDMNPRFKSENILNLELDLPERTTYDYEGPGVDPRVOAA FDCVS Homo sapiens KIFIC Motor Protein MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF DAVYDASSKQADLYDETVRPLIDSVLOGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI PNAFEHIFTHISRSONQOYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL SSFVTKNVKEIEHVMNLGNOTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL GNVIAALAGNRSTHIPYRDSKLTRLLODSLGGNAKTIMVATLGPASHSYDESLSTURFAN RAKNIKNKPRVNEDPKDTLLREFQEE ARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLOEQKERLEEEKAAIQDDRS LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE LKROEIAEOKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIENFIPPEEKNKIM NRL FLDCEEEQWK FQPLVPAGVSQMKKRPTSAVGYKRPISOYARVAMAMGSHPRYRAENIMFLELDVSPPAVE EMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPORPPPSTTHASLASA SLRPATVADHE Align these sequences using NCBI Protein Protein BLAST as you did in problem set 5 and answer the following three questions: al What is the percent identity between these Chlamydomonas and Human Kinesin Il proteins? B) For the proteins that you aligned in the previous question, find the longest contiguous stretch of identical amino acids. What is the sequence of these identical amino acids? c) If you aligned the cDNA sequences for the Chlamydomonas and Human proteins that you aligned above, do you predict that the percent identity would be higher or lower than the percent identity for the alignment of the polypeptide sequences? Explain your answer.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Below are protein sequences for a Kinesin II motor protein from Chlamydomonas reinhardtii and from Homo sapiens.
Chlamydomonas reinhardti Kinesin II Motor Protein
MASGGECVKVAVRCRPLNGKEKGDNRATIVEVDNKTGOVTLNNPKGDEPPKTFTFDNAFD
WNVTQRDVYDVARPIVNSVMDGYNGTIFAYGOTGTGKTHTMEGFPTPELOGIIPNCFDH
VFETVNSSTGKQWMVRASYLEIYNEEVRDLLSKDPKNKLELKEHKDSGVYVKGLNAFVVK
GVPELKNVLEVGKKNRSVGATLMNQDSSRSHSIFTITIETIEOTQAQPEGHIRVGKLNLV
DLAGSERQSKTGATGORLKEATKINLSLSALGNVISALVDGKSGHVPYRDSKLTRLLQDS
LGGNTKTIMCANMGPADWNYDETLSTLRYANRAKNIKNKPKINEDPKDAMLREFQDEIAR
LKAALEAEGGALPEGFATGPGGEIIVEKVVQVPKALDASFLEGMRKDMEEQMKKELASQQ
AAALNDEQLOKVKEEAAAKAKAEAARLEEEKKKAEEEAARMORKQQKIKAEMDKKSLDAE
QIRAEKEALAKKLKAMESKILKGDQAGGLAEVTKKKEEELKRKEQELERRRKEEEEQRKK
IQVMEEQQLAMEDKYKDKADEADOKTKKLKKLWKKFQEVNAEVEDMYKEFQREKEDLLES
IRMLQDQMQLKDMVIEAFIPPEEVQKVMKRAHWDDEREVWVLERLSDIGKRETAQGASRR
PVSASGORRPTSDFAKLANAMGDMNPRFKSENILNLELDLPERTTYDYEGPGVDPRVOAA
FDCVS
Homo sapiens KIFIC Motor Protein
MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF
DAVYDASSKQADLYDETVRPLIDSVLOGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI
PNAFEHIFTHISRSONQOYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL
SSFVTKNVKEIEHVMNLGNOTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG
KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL
GNVIAALAGNRSTHIPYRDSKLTRLLODSLGGNAKTIMVATLGPASHSYDESLSTURFAN
RAKNIKNKPRVNEDPKDTLLREFQEE ARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG
YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLOEQKERLEEEKAAIQDDRS
LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE
LKROEIAEOKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA
EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIENFIPPEEKNKIM NRL FLDCEEEQWK
FQPLVPAGVSQMKKRPTSAVGYKRPISOYARVAMAMGSHPRYRAENIMFLELDVSPPAVE
EMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPORPPPSTTHASLASA
SLRPATVADHE
Align these sequences using NCBI Protein Protein BLAST as you did in problem set 5 and answer the following three questions:
al What is the percent identity between these Chlamydomonas and Human Kinesin Il proteins?
B) For the proteins that you aligned in the previous question, find the longest contiguous stretch of identical amino acids. What is the
sequence of these identical amino acids?
c) If you aligned the cDNA sequences for the Chlamydomonas and Human proteins that you aligned above, do you predict that the
percent identity would be higher or lower than the percent identity for the alignment of the polypeptide sequences? Explain your
answer.
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