Be sure to answer all parts. Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an a-methylene-y -butyrolactone. This heterocyclic ring system is present in some antitumor agents. Do not draw lone pairs in your answers. LDA THF A CH₂I B Br₂ CH, CO,H с Li₂CO3 LiBr DMF & a-methylene- y-butyrolactone
Be sure to answer all parts. Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an a-methylene-y -butyrolactone. This heterocyclic ring system is present in some antitumor agents. Do not draw lone pairs in your answers. LDA THF A CH₂I B Br₂ CH, CO,H с Li₂CO3 LiBr DMF & a-methylene- y-butyrolactone
Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Be sure to answer all parts.
Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an a-methylene-y
-butyrolactone. This heterocyclic ring system is present in some antitumor agents. Do not draw lone
pairs in your answers.
LDA
THF
A
A
OLI
edit structure
CH₂I
B
Br₂
CH,CO,H
edit structure
B
Li₂CO3
LiBr
DMF
a-methylene-
y-butyrolactone
edit structure
C
X
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