Based on the entire Figure 1, what do you notice about the distribution and clustering of the yeast compared to human compared to plant Rab proteins?
Based on the entire Figure 1, what do you notice about the distribution and clustering of the yeast compared to human compared to plant Rab proteins?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Based on the entire Figure 1, what do you notice about the distribution and clustering of the yeast compared to human compared to plant Rab proteins?
Transcribed Image Text:10 changes
66
B
97
77
-Rab39
57
68
A
?-RabB1.b
RabB1.c
RabB1.a
Rab2
Rab4a
Rab14
Rab4b
?
F
93
87
92
D
E
100
70
99
H
72
72
89
59
-RabA5.a
Rab19
53
-RabC1
-Rab18
100
82
-RabA6.a
-RabA6.b
RabA5.b
Rab30
100 RabC2.a
Rab1b
-Ypt1
.Ypt6
99
"RabA1.e
100 Rab11a
Rab11b
-Rab35
98
-RabA1.a
RabA1.f
RabA1.g.
RabA1.i
RabA1.h
RabA5.c
RabA5.e
RabA5.d
RabC2.b
RabA1.d
-RabA1.c
RabA1.b
RabAd
RabA2.b
RabA2.a
-RabD1
72
RabD2.c
RabD2.b
97-Rab1a RabD2.a
72
Rab33a
100-Rab6a
Rab6b
100
-RabA4.a
-RabA3
RabA4.d
-RabA4.c
RabE1.b
RabE1.a
88 RabE1.d
RabE1.e
-Rab33b
RabE1.c
-Ypt52
Rab21
Sec4
Rab5a
Rab5c
-Rab5b
RabA4.b
99
84
100 Ypt31
-RabH1.b
RabF2.a
RabF2.b
Ypt51
-Rab25
-RabH1.e
-RabA4.e
-RabF1
Rab24
Ypt32
Ypt53
Rab 10
61
Ypt10
Rab17
*Rab20
RabH1.d
RabH1.c
-RabH1.a
Rab28
-Rab8a
Rab8b
-Rab13
Rab26
- Rab34
-Rab36
Rab12
Rab22a
Rab22b
-Rab37
Rab15
*
Rab3d
Ypt7
Rab9
*
Rab23
Rab40a
Rab40b
84
Rab7
Rab3a
Rab3c
Rab3b
Rab27a
Rab27b
-Rab29
RabG2
Rab32
-Rab38
RabG3.b
RabG3.a
RabG3.f
RabG3.e
RabG3.d
RabG3.c
Arabidopsis Mammal
RabF1
RabG1
RabF2
RabG2
RabG1
Rab G3
……………***
Rab H1
Rab A1
Rab A2
Rab A4
Rab A3
Rab A6
Rab A5
Rab C2
Rab C1
Rab D1
Rab D2
Rab E1
Rab B1
Rab22
Rab5 Ypt51/52/53
Rab21
Rab17
Rab24
Rab9
Rab32
Rab38
Rab7 Ypt7
Rab29
Rab23
Rab20
Rab11
Rab25
Rab6 Ypt6
Rab33
Rab30
Rab19
Rab 18
Rab1
Rab35
Rab8
Rab13
Rab10
Rab26
S. c.
Rab37
Rab12
Rab3
Rab27
Rab15
Rab40
Ypt10
Rab2
Rab4
Rab14
Rab39
……………….
Ypt1
S. p.
Sec4
Ypt5
Ypt7
Ypt31/32 Ypt3
Ryh1
Ypt1
Ypt2
……………….
RabF1, ARA6, associated with putative endosomal compartments.
Rab22, associated with endosomes.
RabF2b, associated with putative endosomal compartments.
Rab 5, transport from PM to early endosomes and early endosome fusion
Ypt51, transport from PM to early endosomes and between endosomal compartments
Associated with apical PM in epithelial cells
Rab17, transcytosis in epithelial cells
ScYpt7, late-endosome to vacuole and vacuole fusion
Rab7, late endosome to lysosome
Rab9, late endosome to trans-Golgi network
Ypt6, endosome to Golgi
Rab6A, retrograde traffic within the Golgi and from TGN and Golgi to ER
Rab6A', retrograde traffic from early endosome to TGN
Rab11, transport from recycling endosomes to PM, and between endosomes and Golgi
Ypt31/32, transport from late Golgi and to endosomes and PM
Rab25, transport through recycling endosomes
PsRabA4 (Pra3) localised to post-Gogi prevacuolar compartments; distinct from PsRabA3
PsRabA3 (Pra2) localised to post-Gogi prevacuolar compartments; distinct from PsRabA4
AtRabA5.c (ARA4) localised to Golgi and adjacent vesicles
Golgi associated
Golgi associated
Rab18 associated with endosomes, especially in epithelial cells (recycling to PM?)
ScYpt1, ER to Golgi transport and early intra-Golgi transport
Rab1, ER to intermediate-compartment/VTC and early intra-Golgi transport
RabD2a, ER to Golgi transport
Sec4, Golgi to PM (bud site)
Ypt2, Golgi to PM
Rab8, Golgi to basolateral PM in epithelial cells and regulated secretory granule exocytosis
Associated with PM at tight junctions in epithelial cells
Golgi associated
Associated with secretory granules
Associated with secretory granules
Golgi associated
Regulated secretion in neurones and neuroendocrine cells
Melanosome transport in melanocytes
Antagonist of endocytosis at PM
Rab2, maturation of VTC (recycling from VTC to ER?) and intra Golgi traffic
AtRabB1b and tobacco homologue Golgi localised; required for ER-Golgi traffic in pollen tubes
Rab4, recycling from early endosome to PM
Rab14, phagosome associated
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