Barbiturates are prepared by treating a derivative of diethyl malonate with urea in the presence of sodium ethoxide as a catalyst. Following is an equation for the preparation of barbital, a long-duration hypnotic and sedative, from diethyl diethylmalonate and urea. -OEt H,N -NH 1. EtO-Na+ + 2 ELOH 2. Н,О -OEt H,N -NH Diethyl diethylmalonate Urea 5,5-Diethylbarbituric acid (Barbital) Barbital is prescribed under one of a dozen or more trade names.

Q: In charts the pKa of acids are often given instead of the Ka values. For the 5 acids below predict…

A: There are two types of bases/acids. One is strong base/acid which is completely dissociable in into…

Q: Predict the position of the equilibrium for the reaction and provide a brief explanation. (The…

A: The equilibrium of acid base reaction always favours the direction where weaker acid and weaker base…

Q: Identify the conjugate acids of the following bases:  C5H5N (pyridine): _____________________;…

A: Conjugate acid is formed when  base react with H+ or acid

Q: Why is it not possible to predict whether H3PO4 or H2SO3 is the stronger acid?  Show how you can use…

A: The acidic strength is tendency to Lose H+ ion in the solution , experimentally it is determined…

Q: Which molecule is more acidic? H F F F F 2,2-difluoro isomer 3,3-difluoro isomer エ-Z エ-Z

A: This is multiple questions type  So only first question is solved. F is electronegative is group and…

Q: 5) Given the following substances in order of increasing acid strength, (AOCT (99) (HC2H302 (99)k…

A:

Q: Which of the following will be the most basic? Select one: a. 1.0M NO3- b. 1.0M PO43- c. 1.0M SO42-…

A: If acid is strong then corresponding conjugate base is weak base  If acid is weak then corresponding…

Q: | CH;SOH CF3SOH CH3CH2OH CH3COH II IV

A:

Q: Select one or more: O HCO3- H₂PO4 0 Which of these substances is amphoteric? 0 0 0 HS- HELSHE H₂SO4…

A: We have to select the amphoteric substances

Q: 5. Complete the acid/base reaction shown below by providing the conjugate base and conjugate acid.…

A:

Q: 5. Pyridine (CsH5N) is a weak base (a) What is (i.e. look it up) the Kb for pyridine? Then calculate…

A: Kb and pKb are related as pKb = -logKb Ka and Kb are related as Ka×Kb=10-14

Q: Aqueous solutions of which ion would be expected to be more basic? O PO3³- ○ H2PO3 O HPO32-

A: Step 1:A base is a substance that can accept a proton from water to form hydroxide ion   Step 2:Upon…

Q: Calculate the concentration of hydroxide in the following solutions. a) Pure water (pH = 7.00) b)…

A: We know that;  pH + pOH = 14 kb = concentration in product sideconcentration in reactant side…

Q: Which of the following compounds is most acidic? NH3 OH NH2 HO, I II III IV O v O IV III II I

A: Option (A) will be correct choice.

Q: 3. Rank the acidity of the following molecules. OH X NH₂ OH SH

A:

Q: Phenol has a pKa of 9.99.  Calculate the pH of a 0.195 M solution.

A: Given information is as follows: pKa=9.99 Molarity = 0.195 M Determination of Ka from the given pKa…

Q: Identify the neutral form and its conjugate acid/base for both as well. Identify the most polar…

A: In an acidic medium, a basic species gets protonated. A base is a species that is able to accept…

Q: Rank the following in order of increasing acid strength: NH3 < H20 < HF NH3 < HF < H2O HF < H2O < HF…

A: Acidity - the tendency of a compound or molecule to lose Hydrogen or gain Oxygen. Acidity is also…

Q: 4. Given the following: NaOH (c) H₂O (b) NaOH & b (f) a & c O о OF O 6.0 O g O D о J P a (a) BF3 The…

A:

Q: For each value of Ka, calculate the corresponding value of pKa. Which compound is the stronger acid?…

A: pKa of any acid can be calculated as: pKa=-logKa Ka is dissociation constant of an acid. Larger the…

Q: 1. Which groups (if any) can engage in Hydrogen bonding? 2. Which is the most acidic Hydrogen in the…

A: In other words, hydrogen bonding occurs only in compounds having the highly polar F-H, O-H or N-H…

Q: Write the equations for the reaction of the following Bronsted acids with water: (a) HF…

A: Bronsted acid gives H+ ion to the water molecule and bronsted base accept H+ ion from the water…

Q: Rank the following compounds in order of increasing acidity

A:

Q: Hypothetical elements X, Z, and E are nonmetals. X and Z are in the same period and Z and E are in…

A: Now let us examine the factors:Because Z is more electronegative than X, it is more likely to be…

Q: В Но O C, A, B O B, A, C

A: Acidic strength is depends on tendency to lose Hydrogen.  Hydrogen which removes easily, is the most…

Q: In each row, check the box under the compound that can reasonably be expected to be more acidic in…

A: To solve this problem we have to identify the more acidic compounds

Q: Which of the hydrogen atoms is most acidic?

A: Acidity checking for a comound : When hydrogren leave from a compound the negative ion  is…

Q: Arrange the following compounds in terms of their basicity (Strongest base first, weakest base…

A: According this theory 1. Proton (H+) donar is Bronsted acid 2. Proton  (H+) acceptor is Bronsted…

Q: Somew 2. Consider the following compounds. NH

A: The compounds given are conjugate base of CH3COOH and CH3CONH2. So given anions are base.

Q: Explain the difference in pK₂ values. SH OH I || pK₂ 10 pka 18 OII is more acidic because oxygen is…

A:

Q: Sulfuric acid (H2SO4) has a pKa value of -10 and it is almost completely ionized in water. Write the…

A: Lewis structures are diagrams that represent the bonding between atoms in a molecule and the…

Q: Calculate the pH of a 0.105 M solution of ethylenediamine (H,NCH,CH,NH,). The pKa values for the…

A: The pH of 0.105 M ethylene diamine solution is needed to calculated given that the pKa values of…

Acid Base Titration

An acid-base titration is the method of quantitative analysis for determining the concentration of an acid and base by exactly neutralizing it with a standard solution of base or acid having known concentration.