Baclofen, a commonly prescribed muscle relaxant, can exist as either the S or the R enantiomer. The Renantiomer, shown above as its HCl salt, is significantly more potent than the S enantiomer. Answer the following questions related to the optical properties of (R)-baclofen. a) A 100.0 mg sample of (R)-baclofen is dissolved in 50.0 mL of water. The solution is placed in a 1.0 dm polarimeter tube and analyzed using the 589 nm D-line of sodium at 25 °C. The observed rotation is -0.004°. Determine the specific rotation for (R)-
Baclofen, a commonly prescribed muscle relaxant, can exist as either the S or the R enantiomer. The Renantiomer, shown above as its HCl salt, is significantly more potent than the S enantiomer. Answer the following questions related to the optical properties of (R)-baclofen. a) A 100.0 mg sample of (R)-baclofen is dissolved in 50.0 mL of water. The solution is placed in a 1.0 dm polarimeter tube and analyzed using the 589 nm D-line of sodium at 25 °C. The observed rotation is -0.004°. Determine the specific rotation for (R)-
Chapter3: Organic Compounds: Alkanes And Their Stereochemistry
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Problem 51AP
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![Problem 4.16
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X₂ X² Ω·
related to the optical properties of (R)-baclofen.
Baclofen, a commonly prescribed muscle relaxant, can exist as either the S or the R enantiomer.
NH₂
The R enantiomer, shown above as its HCl salt, is significantly more potent than the S enantiomer. Answer the following questions
• HCI
baclofen.
CO₂H
a) A 100.0 mg sample of (R)-baclofen is dissolved in 50.0 mL of water. The solution is placed in a 1.0 dm polarimeter tube and
(+/-)
analyzed using the 589 nm D-line of sodium at 25 °C. The observed rotation is -0.004°. Determine the specific rotation for (R)-
0.002
X
O](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd7eccf86-48c8-4517-b297-2a017ba5d306%2F9977844a-ac4b-4c13-816b-19bfe23be72c%2Fo8rb9o_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Problem 4.16
Homework Answered
Fill in the Blanks
Type your answers in all of the blanks and submit
X₂ X² Ω·
related to the optical properties of (R)-baclofen.
Baclofen, a commonly prescribed muscle relaxant, can exist as either the S or the R enantiomer.
NH₂
The R enantiomer, shown above as its HCl salt, is significantly more potent than the S enantiomer. Answer the following questions
• HCI
baclofen.
CO₂H
a) A 100.0 mg sample of (R)-baclofen is dissolved in 50.0 mL of water. The solution is placed in a 1.0 dm polarimeter tube and
(+/-)
analyzed using the 589 nm D-line of sodium at 25 °C. The observed rotation is -0.004°. Determine the specific rotation for (R)-
0.002
X
O
![b) What is the specific rotation of (S)-baclofen under the same conditions? +
0.002
You are incorrect
X
0
O
c) At what concentration would the observed rotation of (R)-baclofen be -0.08°? 40
You are incorrect
d) What would the observed rotation be if 30.0 mg of (R)-baclofen were dissolved in 10.0 mL of water?
X (+/-)
You are correct
0.006
You are correct
You are incorrect
C
(+/-)
X g/100 mL](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd7eccf86-48c8-4517-b297-2a017ba5d306%2F9977844a-ac4b-4c13-816b-19bfe23be72c%2Fz2gki4e_processed.jpeg&w=3840&q=75)
Transcribed Image Text:b) What is the specific rotation of (S)-baclofen under the same conditions? +
0.002
You are incorrect
X
0
O
c) At what concentration would the observed rotation of (R)-baclofen be -0.08°? 40
You are incorrect
d) What would the observed rotation be if 30.0 mg of (R)-baclofen were dissolved in 10.0 mL of water?
X (+/-)
You are correct
0.006
You are correct
You are incorrect
C
(+/-)
X g/100 mL
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