background information: The slow block to polyspermy involves a permanent modification of the egg surface, usually through exocytosis of the cortical granules. In the 1970s, Dave Epel carried out experiments that led to the conclusion that a Ca2+ rise in the egg is both necessary and sufficient to trigger cortical granule exoctyosis (CGE).        Experiment (b) – Dr. Epel injects a small amount of Ca2+ into unfertilized eggs and observes CGE almost immediately   For the experiment above, is it an example of correlation, loss-of-function or gain-of function? Then, indicate the predicted result.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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background information: The slow block to polyspermy involves a permanent modification of the egg surface, usually through exocytosis of the cortical granules. In the 1970s, Dave Epel carried out experiments that led to the conclusion that a Ca2+ rise in the egg is both necessary and sufficient to trigger cortical granule exoctyosis (CGE). 

 

 

 

Experiment (b) – Dr. Epel injects a small amount of Ca2+ into unfertilized eggs and observes CGE almost immediately

 

For the experiment above, is it an example of correlation, loss-of-function or gain-of function? Then, indicate the predicted result.

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