Homework Help is Here – Start Your Trial Now!
Science
Biology
b. How is the inheritance pattern of Jervell and Lange-Nielsen syndrome similar to that of familial hypercholesterolemia? Answer c. How possible is it that Tina would not inherit either the serious or asymptomatic form? Answer

b. How is the inheritance pattern of Jervell and Lange-Nielsen syndrome similar to that of familial hypercholesterolemia? Answer c. How possible is it that Tina would not inherit either the serious or asymptomatic form? Answer

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question

What unusual phenomenon is at work in each of the following disorders?

 

b. How is the inheritance pattern of Jervell and Lange-Nielsen syndrome similar to that of familial hypercholesterolemia? Answer c. How possible is it that Tina would not inherit either the seriou or asymptomatic form? Answer
Transcribed Image Text:b. How is the inheritance pattern of Jervell and Lange-Nielsen syndrome similar to that of familial hypercholesterolemia? Answer c. How possible is it that Tina would not inherit either the seriou or asymptomatic form? Answer
b. Two couples are heterozygous for genes that cause albinism, but each gene specifies a different enzyme in the biochemical pathway for skin pigment synthesis. Their children, thus, do not face a 25% risk of having albinism. Answer c. Clara has severe neurofibromatosis type I. She has brown spots on her skin and several large tumors beneath her skin. A gene test shows that her son has inherited the disease-causing autosomal dominant allele, but he has no symptoms. Answer d. Mateo, an apparently healthy 24-year-old basketball player, dies when his aorta ruptures. A younger brother is nearsighted and has long and thin fingers, and an older sister is extremely tall, with long arms and legs. The older sister, too, has a weakened aorta. All of these siblings have Marfan syndrome. Answer e. The B allele confers black coat color and the b allele brown coat color in Labrador dogs. When another gene, E, is inherited, the coat is golden no matter what the B phenotype is. A dog of genotype ee expresses the black phenotype. Answer 5. Connie Winslow is deaf. When she was old enough to attend school, she began having fainting spells, especially when she became excited. Her parents took her to a neurologist, who checked Connie's heart and diagnosed long-QT syndrome with deafness also called Jervell and Lange-Nielsen syndrome. This is a severe form of inherited heartbeat irregularity that can be fatal. Seven different genes can cause long-QT syndrome. The Winslows visited a medical geneticist, who discovered that each had a mild heartbeat irregularity that did not produce symptoms. Connie's parents had normal hearing. Connie's younger brother Jim was also hearing-impaired and suffered night terrors, but had so far not fainted during the day. Like Connie, he had the full syndrome. Tina, still a baby, was also tested. She did not have either form of the family's illness; her heartbeat was normal.
Transcribed Image Text:b. Two couples are heterozygous for genes that cause albinism, but each gene specifies a different enzyme in the biochemical pathway for skin pigment synthesis. Their children, thus, do not face a 25% risk of having albinism. Answer c. Clara has severe neurofibromatosis type I. She has brown spots on her skin and several large tumors beneath her skin. A gene test shows that her son has inherited the disease-causing autosomal dominant allele, but he has no symptoms. Answer d. Mateo, an apparently healthy 24-year-old basketball player, dies when his aorta ruptures. A younger brother is nearsighted and has long and thin fingers, and an older sister is extremely tall, with long arms and legs. The older sister, too, has a weakened aorta. All of these siblings have Marfan syndrome. Answer e. The B allele confers black coat color and the b allele brown coat color in Labrador dogs. When another gene, E, is inherited, the coat is golden no matter what the B phenotype is. A dog of genotype ee expresses the black phenotype. Answer 5. Connie Winslow is deaf. When she was old enough to attend school, she began having fainting spells, especially when she became excited. Her parents took her to a neurologist, who checked Connie's heart and diagnosed long-QT syndrome with deafness also called Jervell and Lange-Nielsen syndrome. This is a severe form of inherited heartbeat irregularity that can be fatal. Seven different genes can cause long-QT syndrome. The Winslows visited a medical geneticist, who discovered that each had a mild heartbeat irregularity that did not produce symptoms. Connie's parents had normal hearing. Connie's younger brother Jim was also hearing-impaired and suffered night terrors, but had so far not fainted during the day. Like Connie, he had the full syndrome. Tina, still a baby, was also tested. She did not have either form of the family's illness; her heartbeat was normal.
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Stress
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS