(b) For the following set of E2 reactions, draw the major organic product and indicate which reaction occurs at the faster rate (same expected products for both, can draw once) CH3 H3C H3C CH3 г CH3 CH3O CH3

Draw the free energy diagram for each of the reactions in Problem 8.33. For each diagram, include and label the overall reactants, overall products, all intermediates, and all transition states.

Be sure to answer all parts. Draw all constitutional isomers formed in the E2 reaction below and predict the major product using the Zaitsev rule. OH The tetrasubstituted product is: draw structure . The trisubstituted product is: draw structure.. The disubstituted product is: draw structure. The major product is the (select) substituted product.

(c) What sequence of reactions could be used to ensure the following transformation? ? H

Heating an alcohol in the presence of sulfuric or phosphoric acid will cause a dehydration to occur: the removal of the elements of water from a molecule, forming an alkene. The reaction usually follows an E1 mechanism. The SN1 pathway is suppressed, both by heating the reaction mixture (more energy promotes the elimination pathway) and by using a strong acid whose conjugate base is a poor nucleophile.   Draw curved arrow(s) to show how the alcohol reacts with phosphoric acid.

Draw a stepwise, detailed mechanism for the following reaction. CH3NH2 N-CH3 CH,NH, Cr (excess)

Describe the following chemical reactions as SN1, SN2, E1, and E2. Draw a curved arrow mechanism for each reaction.

Q12. (1bremeetblbenzene 1 ydergOesan elimination following an E1 mechanism. Fill in the following synthetic scheme by drawing the structure of intermediate 2 and product 3. The chemical formula of product 3 is provided as guidance.

4) Draw the complete electron-pushing arrow mechanism for the following reductions. Explain, using resonance contributors, the regiochemistry that results in each case. ỌMe Na, MeOH ? NH3 CHO Na, MeOH ? NH3

Determine whether the following will proceed via SN1, SN2, E1 or E2 reaction. Draw the major product.