autosomal recessive autosomal dominant X-linked dominant X-linked recessive Y-linked

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Identify the type of trait(s) in the pedigree below *
autosomal recessive
autosomal dominant
X-linked dominant
X-linked recessive
Y-linked
Transcribed Image Text:Identify the type of trait(s) in the pedigree below * autosomal recessive autosomal dominant X-linked dominant X-linked recessive Y-linked
Expert Solution
PEDIGREE ANALYSIS

Answer: A pedigree is a fmily tree or chart made of symbols and lines that represent a person genetic family history. In oedigree, symbols represent people and lines represent genetic relationships. the pedigree is a visual tool for documenting the biological relationship in families and determine the mode of inheritance ( dominant , recessive etc) of genetic diseases. pedigrees are most often constructed by medical genetisists or genetic counselors.

VARIOUS TYPES OF PATTERNS IN PEDIGREE:

AUTOSOMAL RECESSIVE INHERITANCE:

  • traits often skip generations
  • an almost equal number of affected males and females
  • if both parents are affected , all children should be affected
  • most affected individuals have unaffected parents.

AUTOSOMAL DOMINANT INHERITANCE:

  • traits should not skip generations
  • an affected person mating with an unaffected person should produce approx 50% affected offspring
  • the distribution of the traits among the offspring should be equal
  • transmitted by either sex

X- LINKED RECESSIVE INHERITANCE

  • most affected individuals are male
  • affected males should results from mothers who are affected or who are known to be carriers
  • affected females come from affected father and affected or carrier mother
  • the sons of affected mothers should be affected
  • approx half the sons of carriers should be affected

X-LINKED DOMINANT INHERITANCE

  • the trait does not skip generations
  • affected males must come from affected mothers
  • approx half the children of an affected heterozygous females are affected
  • affected females come from affected mother or father
  • all the daughters , but none of the sons, of an affected father are affected

Y-LINKED INHERITANCE

  • affects only males
  • affected males always have an affected father
  • all sons of an affected man are affected
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