Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-COA reductase. See"Connections to Biological Chemistry" one synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used. Draw the structures of synthetic intermedi- ates A and B. In -Cl NaCN НО. A B DMSO Pyridine
Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works by inhibiting an enzyme called HMG-COA reductase. See"Connections to Biological Chemistry" one synthesis of atorvastatin that produces the desired single enantiomer of the final product, the following reagents are used. Draw the structures of synthetic intermedi- ates A and B. In -Cl NaCN НО. A B DMSO Pyridine
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works
by inhibiting an enzyme called HMG-COA reductase. See"Connections to Biological
Chemistry"
one synthesis of atorvastatin that produces the desired single enantiomer of the final
product, the following reagents are used. Draw the structures of synthetic intermedi-
ates A and B.
In
-Cl
NaCN
НО.
A
B
DMSO
Pyridine](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F814144eb-833b-486f-a7b1-24152c85f90a%2F512f30fb-b1b1-4de5-b326-aef48c6d612a%2Furtgfqh.jpeg&w=3840&q=75)
Transcribed Image Text:Atorvastatin (Lipitor) is used to decrease patient serum cholesterol levels. It works
by inhibiting an enzyme called HMG-COA reductase. See"Connections to Biological
Chemistry"
one synthesis of atorvastatin that produces the desired single enantiomer of the final
product, the following reagents are used. Draw the structures of synthetic intermedi-
ates A and B.
In
-Cl
NaCN
НО.
A
B
DMSO
Pyridine
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