At some point during the synthesis of a target molecule, it may be necessary to protect an-OH group (i.e., to prevent its reacting). In addition to the trimethylsilyl, tert-butyl- dimethylsilyl, and other trialkylsilyl groups dropyranyl group a protecting group. and the tetrahy- , the ethoxyethyl group may also be used as an ethoxyethyl ArSO,H group RCH,OH + RCH,-O Ethyl vinyl ether

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Propose a mechanism for the acid-catalyzed formation of the ethoxyethyl protecting group.

At some point during the synthesis of a target molecule, it may be necessary to protect
an-OH group (i.e., to prevent its reacting). In addition to the trimethylsilyl, tert-butyl-
dimethylsilyl, and other trialkylsilyl groups
dropyranyl group
a protecting group.
and the tetrahy-
, the ethoxyethyl group may also be used as
an ethoxyethyl
ArSO,H
group
RCH,OH +
RCH,-O
Ethyl vinyl ether
Transcribed Image Text:At some point during the synthesis of a target molecule, it may be necessary to protect an-OH group (i.e., to prevent its reacting). In addition to the trimethylsilyl, tert-butyl- dimethylsilyl, and other trialkylsilyl groups dropyranyl group a protecting group. and the tetrahy- , the ethoxyethyl group may also be used as an ethoxyethyl ArSO,H group RCH,OH + RCH,-O Ethyl vinyl ether
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