At pH 3, the R-group of histidine is_______ and O protonated; neutral O protonated; positively charged O protonated; negatively charged O deprotonated; neutral O deprotonated; positively charged
At pH 3, the R-group of histidine is_______ and O protonated; neutral O protonated; positively charged O protonated; negatively charged O deprotonated; neutral O deprotonated; positively charged
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:At pH 3, the R-group of histidine is
O protonated; neutral
O protonated; positively charged
O protonated; negatively charged
O deprotonated; neutral
O deprotonated; positively charged
and
Expert Solution
Step 1
Histidine (His or H) is an essential amino acids used in the biosynthesis of proteins. It contains an alpha amino group and a carboxyl group (which is in the deprotonated –COO− form under biological conditions), and an imidazole side chain (which is partially protonated), classifying it as a positively charged amino acid at physiological pH.
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