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Ascll is an activating transcription factor containing a DNA binding domain and an activation domain. Ascil induces neuronal differentiation. A truncated Asci1 lacking the DNA binding domain but with an intact activation domain will: Bind to DNA, activate transcription, and differentiate cells into neurons Bind to DNA, not activate transcription, and not differentiate cells into neurons Not bind to DNA, activate transcription, and differentiate cells into neurons O Not bind to DNA, not activate transcription and differentiate cells into neurons O Not bind to DNA, not activate transcription, and will not differentiate cells into neurons

Ascll is an activating transcription factor containing a DNA binding domain and an activation domain. Ascil induces neuronal differentiation. A truncated Asci1 lacking the DNA binding domain but with an intact activation domain will: Bind to DNA, activate transcription, and differentiate cells into neurons Bind to DNA, not activate transcription, and not differentiate cells into neurons Not bind to DNA, activate transcription, and differentiate cells into neurons O Not bind to DNA, not activate transcription and differentiate cells into neurons O Not bind to DNA, not activate transcription, and will not differentiate cells into neurons

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Ascl1 Functionality in Neuronal Differentiation** Ascl1 is an activating transcription factor comprising a DNA binding domain and an activation domain. It plays a crucial role in inducing neuronal differentiation. **Scenario: Truncated Ascl1** Consider a scenario where Ascl1 is truncated, lacking the DNA binding domain but retaining an intact activation domain. In this case, the Ascl1 will: - **Not bind to DNA** - **Not activate transcription** - **Will not differentiate cells into neurons** This is due to the absence of the DNA binding domain, which is essential for initiating transcription and subsequent neuronal differentiation.
Transcribed Image Text:**Ascl1 Functionality in Neuronal Differentiation** Ascl1 is an activating transcription factor comprising a DNA binding domain and an activation domain. It plays a crucial role in inducing neuronal differentiation. **Scenario: Truncated Ascl1** Consider a scenario where Ascl1 is truncated, lacking the DNA binding domain but retaining an intact activation domain. In this case, the Ascl1 will: - **Not bind to DNA** - **Not activate transcription** - **Will not differentiate cells into neurons** This is due to the absence of the DNA binding domain, which is essential for initiating transcription and subsequent neuronal differentiation.
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