Question 49As the strands are synthesized in replication, which of the following is true?A) the strand that shows the Okazaki fragments is synthesized in the 3'-5' direction.the leading strand is synthesized continuously from the 5' to 3' direction while the other strand is synthesizedBdiscontinuously in the 3' to 5' direction(c) both strands are synthesized continuouslyD both strands are synthesized in the 5' to 3' direction

The process of in which DNA molecule produce exact copy or replica of itself is known as the…

Answered: As the strands are synthesized in…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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For the following steps in DNA replication, name the prokaryotic and eukaryotic enzymes (in that order!) that perform the task listed: Question 33 options: Tethering a polymerase to DNA (prokaryotes) Removing supercoils (eukaryotes) Removing supercoils (prokaryotes) Lagging strand replication (eukaryotes) Lagging strand replication (prokaryotes) Tethering a polymerase to DNA (eukaryotes) Stabilizing single-stranded DNA (prokaryotes) Stabilizing single-stranded DNA (eukaryotes) 1. DNA Pol III 2. DNA Pol Delta () 3. DNA Pol Epsilon () 4. Helicase 5. Topoisomerase (type I or II) 6. Beta clamp 7. PCNA 8. SSB 9. RPA 10. DNA Pol I 11. Ligase
Briefly explain why DNA replication produces two daughter strands that are identical to each other and to the parent DNA.
Explain how DNA gyrase works.
Deoxyadenylate residues in DNA undergo deamination fairly readily, as do deoxycytidylate residues. (a) What is the product of dAMP deamination? (b) The deamination product is known to base-pair with A, C, or T. What would be the genetic consequences if this deaminated site in DNA were not repaired and if it paired with C on the next round of replication?
In eukaryotes, the Replication factor C (RFC) is a clamp loader. In the absence of RFC, what would be the consequences to the outcome of DNA replication? Explain.
Depurination of purine bases results in an apurinic site. Assume a single depurination event occurs in the GC base pair of the sequence below and is not repaired. Then, if two rounds of replication occur, which of the following DNA sequences will exist after two rounds of replication? Remember that when DNA polymerases encounter an apurinic site, most often an A is incorporated into the newly synthesized strand. Assume this is true for the sequence below. ...TACT... ...ATGA... Question 7 Select one or more: a) ...TAGT... ...ATCA... b) ...TACT... ...ATGA... c)...TAAT... ...ATTA... d) ...TAAT... ...AT_A... . e) ...TA_T... ...ATAA... f)...TATT... ...ATAA...
Describe the functions of the following proteins during DNA replication: (i) Polymerase delta (ii) PCNA (iii) Telomerase
describe specifically how protein tertiary structure facilitates DNA replication.
In both leading and lagging strand synthesis, DNA replication always proceeds in a certain direction. What direction is this? Explain how oligonucleotide primers in the Polymerase Chain Reaction work (PCR)
Depurination of purine bases results in an apurinic site. Assume a single depurination event occurs in the GC base pair of the sequence below and is not repaired. Then, if two rounds of replication occur, which of the following DNA sequences will exist after two rounds of replication? Remember that when DNA polymerases encounter an apurinic site, most often an A is incorporated into the newly synthesized strand. Assume this is true for the sequence below. ...TACT... ...ATGA... Question 7 Select one or more: ...TAGT... ...ATCA... 1. ...TACT... ...ATGA... 2. ...TAAT... ...ATTA... 3. ...TAAT... ...AT_A... 4. ...TA_T... ...ATAA... 5. ...TATT... ...ATAA...
Consider the following segment of DNA, which is part of a linear chromosome: LEFT 5’.…TGACTGACAGTC….3’ 3’.…ACTGACTGTCAG….5’ RIGHT During DNA replication, this double-strand molecule is separated from the right to the left into two single strands and the replisome is moving from the right to the left of the segment. The replisome is approaching to a chromosomal end on the left. Considering this left chromosomal end, if without telomerase, the newly synthesized daughter DNA of ___________ will be shortened? neither top or bottom strand both top and bottom strands the top strand the bottom strand
Name an important difference in the replication of circular DNA versus linear double-stranded DNA.

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