As men age, their testosterone levels gradually decrease. This may cause a reduction in lean body mass, an increase in fat, and other undesirable changes. Do testosterone supplements reverse some of these effects? A study in the Netherland assigned 237 men aged 60 to 80 with low or low-normal testosterone levels to either a testosterone supplement or a placebo. The report in the Journal of the American Medical Association described the study as a "double-blind, randomized, placebo-controlled trial." How would you explain each of these terms to someone who knows no statistics? Select the correct meaning of the term "double-blind". Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to the subject. Double-blind means that the subjects and those responsible for assessing the effectiveness of the treatment were not known to each other. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to both the subject and those responsible for assessing the effectiveness of that treatment. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to those responsible for assessing the effectiveness of that treatment.

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As men age, their testosterone levels gradually decrease. This may cause a reduction in lean body mass, an increase in
fat, and other undesirable changes. Do testosterone supplements reverse some of these effects? A study in the Netherlands
assigned 237 men aged 60 to 80 with low or low-normal testosterone levels to either a testosterone supplement or a
placebo. The report in the Journal of the American Medical Association described the study as a "double-blind,
randomized, placebo-controlled trial." How would you explain each of these terms to someone who knows no statistics?
Select the correct meaning of the term "double-blind".
Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to the subject.
Double-blind means that the subjects and those responsible for assessing the effectiveness of the treatment were not
known to each other.
Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to both the
subject and those responsible for assessing the effectiveness of that treatment.
O Double-blind means that the treatment–testosterone or placebo-assigned to a subject was unknown to those
responsible for assessing the effectiveness of that treatment.
Transcribed Image Text:As men age, their testosterone levels gradually decrease. This may cause a reduction in lean body mass, an increase in fat, and other undesirable changes. Do testosterone supplements reverse some of these effects? A study in the Netherlands assigned 237 men aged 60 to 80 with low or low-normal testosterone levels to either a testosterone supplement or a placebo. The report in the Journal of the American Medical Association described the study as a "double-blind, randomized, placebo-controlled trial." How would you explain each of these terms to someone who knows no statistics? Select the correct meaning of the term "double-blind". Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to the subject. Double-blind means that the subjects and those responsible for assessing the effectiveness of the treatment were not known to each other. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to both the subject and those responsible for assessing the effectiveness of that treatment. O Double-blind means that the treatment–testosterone or placebo-assigned to a subject was unknown to those responsible for assessing the effectiveness of that treatment.
Select the correct meaning of the term "randomized experiment".
Randomized experiment means that patients were randomly assigned to receive either the testosterone supplement
or a placebo.
O Randomized experiment means that the patients did not know which study they were enrolled in.
Randomized experiment means that the subjects were selected randomly from the population of men aged 60 to 80
with low or low-normal testosterone levels.
Randomized experiment means that the subjects were selected randomly from the general population of all men.
Select the correct meaning of the term "placebo-controlled trial".
Placebo-controlled means that the study is an experiment rather than an observational study.
Placebo-controlled means that the placebo group showed the same results as the treatment group.
Placebo-controlled means that some of the subjects were given placebos.
Placebo-controlled means that the study did not use a placebo group in its design.
Transcribed Image Text:Select the correct meaning of the term "randomized experiment". Randomized experiment means that patients were randomly assigned to receive either the testosterone supplement or a placebo. O Randomized experiment means that the patients did not know which study they were enrolled in. Randomized experiment means that the subjects were selected randomly from the population of men aged 60 to 80 with low or low-normal testosterone levels. Randomized experiment means that the subjects were selected randomly from the general population of all men. Select the correct meaning of the term "placebo-controlled trial". Placebo-controlled means that the study is an experiment rather than an observational study. Placebo-controlled means that the placebo group showed the same results as the treatment group. Placebo-controlled means that some of the subjects were given placebos. Placebo-controlled means that the study did not use a placebo group in its design.
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