Arrange the steps in the base excision repair process. Write the capital letter corresponding each step on the space provided. A. An enzyme called AP (apurinic/apyrimidinic) endonuclease makes an incision at the abasic site, creating a break, or nick, in the strand of DNA. B. There is addition of new nucleotides by DNA polymerase and sealing of nicks by DNA ligase. C. Identification of the mutated base from the DNA helix by an enzyme known as DNA glycosylase occurs. D. Removal of a base from its sugar happens once DNA glycosylase recognizes the damaged base. E. The phosphodiester backbone is cut after the resulting gap is repaired. Step 1: Step 2: Step Step 4: Step 5:
Arrange the steps in the base excision repair process. Write the capital letter corresponding each step on the space provided. A. An enzyme called AP (apurinic/apyrimidinic) endonuclease makes an incision at the abasic site, creating a break, or nick, in the strand of DNA. B. There is addition of new nucleotides by DNA polymerase and sealing of nicks by DNA ligase. C. Identification of the mutated base from the DNA helix by an enzyme known as DNA glycosylase occurs. D. Removal of a base from its sugar happens once DNA glycosylase recognizes the damaged base. E. The phosphodiester backbone is cut after the resulting gap is repaired. Step 1: Step 2: Step Step 4: Step 5:
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:Arrange the steps in the base excision repair process. Write the capital letter corresponding each step on the space provided.
(apurinic/apyrimidinic) endonuclease makes an incision at the abasic site, creating a break, or nick, in the
A. An enzyme called AP
strand of DNA.
B. There is addition of new nucleotides by DNA polymerase and sealing of nicks by DNA ligase.
C. Identification of the mutated base from the DNA helix by an enzyme known as DNA glycosylase occurs.
D. Removal of a base from its sugar happens once DNA glycosylase recognizes the damaged base.
E. The phosphodiester backbone is cut after the resulting gap is repaired.
Step 1:
Step 2:
Step 3:
Step 4:
Step 5:
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