Appendix A - Commercially available analgesics. No: Commercial Aspirin Caffeine Acetaminophen Ibu name Bayer Aspirin Generic Aspirin Excedrin Anacin No-doz Tylenol Motrin 1 2 3 X X X X X 7

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my unknown # is 5.

### Appendix A - Commercially Available Analgesics

The following table lists various commercially available analgesics and their active ingredients:

| No. | Commercial Name   | Aspirin | Caffeine | Acetaminophen | Ibuprofen |
|-----|--------------------|---------|----------|---------------|-----------|
| 1   | Bayer Aspirin      | X       |          |               |           |
| 2   | Generic Aspirin    | X       |          |               |           |
| 3   | Excedrin           | X       | X        | X             |           |
| 4   | Anacin             | X       | X        |               |           |
| 5   | No-doz             |         | X        |               |           |
| 6   | Tylenol            |         |          | X             |           |
| 7   | Motrin             |         |          |               | X         |

### Table 1: Thin Layer Chromatography (TLC) Analysis

The following table shows data for the distance traveled by different substances in a TLC analysis, alongside their Retention Factor (Rf) values:

| Known         | Distance Travelled (cm) | Rf Value   |
|---------------|--------------------------|------------|
| Solvent       | 5.2                      | -          |
| Aspirin       | 3.0                      | 0.58       |
| Acetaminophen | 1.8                      | 0.35       |
| Caffeine      | 0.40                     | 0.08       |
| Ibuprofen     | 3.5                      | 0.67       |

#### Explanation of Graphs and Tables:

**Appendix A - Commercially Available Analgesics:**
- This table categorizes seven different commercially available analgesic products based on their active ingredients including Aspirin, Caffeine, Acetaminophen, and Ibuprofen.
- The 'X' mark in the respective columns indicates the presence of that specific component in the commercial product.

**Table 1 - TLC Analysis:**
- This table presents the results of a Thin Layer Chromatography experiment, which separates compounds based on their affinity to the mobile and stationary phases.
- The 'Distance Traveled' column shows how far each known substance moved on the TLC plate.
- The 'Rf Value' (Retention Factor) is calculated by the formula \( Rf = \frac
Transcribed Image Text:### Appendix A - Commercially Available Analgesics The following table lists various commercially available analgesics and their active ingredients: | No. | Commercial Name | Aspirin | Caffeine | Acetaminophen | Ibuprofen | |-----|--------------------|---------|----------|---------------|-----------| | 1 | Bayer Aspirin | X | | | | | 2 | Generic Aspirin | X | | | | | 3 | Excedrin | X | X | X | | | 4 | Anacin | X | X | | | | 5 | No-doz | | X | | | | 6 | Tylenol | | | X | | | 7 | Motrin | | | | X | ### Table 1: Thin Layer Chromatography (TLC) Analysis The following table shows data for the distance traveled by different substances in a TLC analysis, alongside their Retention Factor (Rf) values: | Known | Distance Travelled (cm) | Rf Value | |---------------|--------------------------|------------| | Solvent | 5.2 | - | | Aspirin | 3.0 | 0.58 | | Acetaminophen | 1.8 | 0.35 | | Caffeine | 0.40 | 0.08 | | Ibuprofen | 3.5 | 0.67 | #### Explanation of Graphs and Tables: **Appendix A - Commercially Available Analgesics:** - This table categorizes seven different commercially available analgesic products based on their active ingredients including Aspirin, Caffeine, Acetaminophen, and Ibuprofen. - The 'X' mark in the respective columns indicates the presence of that specific component in the commercial product. **Table 1 - TLC Analysis:** - This table presents the results of a Thin Layer Chromatography experiment, which separates compounds based on their affinity to the mobile and stationary phases. - The 'Distance Traveled' column shows how far each known substance moved on the TLC plate. - The 'Rf Value' (Retention Factor) is calculated by the formula \( Rf = \frac
**Worksheet: TLC Analysis of Analgesic Drugs**

### Table 2: Complete Data
*Don't forget to write the unknown number.*

| Known Mixture | Rf Value (Calculated from Table 1) | Unknown # 5 | Rf Value | Possible Ingredients in the Unknown |
|---------------|------------------------------------|-------------|----------|-------------------------------------|
| Spot 1        |                                    | Spot 1      |          |                                     |
| Spot 2        |                                    | Spot 2      |          |                                     |
| Spot 3        |                                    | Spot 3      |          |                                     |
| Spot 4        |                                    | Spot 4      |          |                                     |

**Instructions:**
1. Identify the spots from the known mixture.
2. Calculate and record the Rf values from Table 1.
3. Match the spots from the unknown sample with the known spots to determine the possible ingredients.

In the table, the column "Rf Value (Calculated from Table 1)" requires the calculated Rf values of the spots from the known mixture. The "Unknown # 5" column is for noting the observed spots of the unknown sample. After recording the necessary Rf values, compare them and deduce the possible ingredients contained in the unknown sample under the "Possible ingredients in the unknown" column.

This exercise is essential for understanding the principles behind Thin Layer Chromatography (TLC) and the application of Rf value calculations in identifying substances within a mixture.
Transcribed Image Text:**Worksheet: TLC Analysis of Analgesic Drugs** ### Table 2: Complete Data *Don't forget to write the unknown number.* | Known Mixture | Rf Value (Calculated from Table 1) | Unknown # 5 | Rf Value | Possible Ingredients in the Unknown | |---------------|------------------------------------|-------------|----------|-------------------------------------| | Spot 1 | | Spot 1 | | | | Spot 2 | | Spot 2 | | | | Spot 3 | | Spot 3 | | | | Spot 4 | | Spot 4 | | | **Instructions:** 1. Identify the spots from the known mixture. 2. Calculate and record the Rf values from Table 1. 3. Match the spots from the unknown sample with the known spots to determine the possible ingredients. In the table, the column "Rf Value (Calculated from Table 1)" requires the calculated Rf values of the spots from the known mixture. The "Unknown # 5" column is for noting the observed spots of the unknown sample. After recording the necessary Rf values, compare them and deduce the possible ingredients contained in the unknown sample under the "Possible ingredients in the unknown" column. This exercise is essential for understanding the principles behind Thin Layer Chromatography (TLC) and the application of Rf value calculations in identifying substances within a mixture.
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