Analysis of a octapeptide revealed the presence of the following products: 2 Arg, 1 Gly, 1 Met, 1 Trp, 1 Tyr, 1 Phe, 1 Lys The following facts were observed: a. Edman degradation gave: NH b. CNBr treatment yielded a pentapeptide, and a tripeptide containing phenylalanine. c. Chymotrypsin treatment yielded a tetrapeptide containing a C-terminal indole amino acid and two dipeptides d. Trypsin treatment yielded a tetrapeptide, a dipeptide, and free Lys and Phe e. Clostripain yielded a pentapeptide, a dipeptide, and free Phe. What is the amino acid sequence of this octapeptide? (Use the three letter codes for amino acids in your answer, and if there is more than one possible sequence just enter one. Separate amine acids using spaces.)

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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3
Analysis of a octapeptide revealed the presence of the following products:
erences
2 Arg, 1 Gly, 1 Met, 1 Trp, 1 Tyr, 1 Phe, 1 Lys
The following facts were observed:
a. Edman degradation gave:
NH
b. CNBr treatment yielded a pentapeptide, and a tripeptide containing phenylalanine.
c. Chymotrypsin treatment yielded a tetrapeptide containing a C-terminal indole amino acid and two dipeptides
d. Trypsin treatment yielded a tetrapeptide, a dipeptide, and free Lys and Phe.
e. Clostripain yielded a pentapeptide, a dipeptide, and free Phe.
What is the amino acid sequence of this octapeptide?
(Use the three letter codes for amino acids in your answer, and il there is more than one possible sequence just enter one. Separate amine acids ansing
spaces.)
Transcribed Image Text:Analysis of a octapeptide revealed the presence of the following products: erences 2 Arg, 1 Gly, 1 Met, 1 Trp, 1 Tyr, 1 Phe, 1 Lys The following facts were observed: a. Edman degradation gave: NH b. CNBr treatment yielded a pentapeptide, and a tripeptide containing phenylalanine. c. Chymotrypsin treatment yielded a tetrapeptide containing a C-terminal indole amino acid and two dipeptides d. Trypsin treatment yielded a tetrapeptide, a dipeptide, and free Lys and Phe. e. Clostripain yielded a pentapeptide, a dipeptide, and free Phe. What is the amino acid sequence of this octapeptide? (Use the three letter codes for amino acids in your answer, and il there is more than one possible sequence just enter one. Separate amine acids ansing spaces.)
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