An O positive newborn is severely jaundiced due to HDFN and has a positive DAT. Mother is O negative with an anti-K. The physician has ordered an exchange transfusion for this newborn. What blood should be given to this newborn? Does this blood need to be crossmatched and if so, how would that be done?
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An O positive newborn is severely jaundiced due to HDFN and has a positive DAT. Mother is O negative with an anti-K. The physician has ordered an exchange transfusion for this newborn. What blood should be given to this newborn? Does this blood need to be crossmatched and if so, how would that be done?
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- Below are the ABO and Rh blood types of some couples. If during birth some blood is exchaged between the mother and the first newborn, the second newborn of which couple has the LEAST chance for suffering from hemolytic disease of the newborn due to Rh incompatibility? Consider both Rh and ABO incompatibilities. A. Wife B -, husband O + B. Wife AB -, husband AB + C. Wife AB -, husband O+ D. Wife O -, husband B + E. Wife A -, husband O+What causes hemolytic disease of the newborn (erythroblastosis fetalis)? Why does the condition not arise in cases of ABO incompatibility?Select all the statements below that are true regarding hemolytic disease of the newborn. If a mother is Rh- and becomes sensitized with anti-Rh antibodies, all subsequent children will be affected Hemolytic disease of the newborn can only occur if the mother is Rh-. If an Rh- mother becomes sensitized, only her subsequent children with Rh+ blood will be affected If a mother is Rh- and her first child is Rh+, the child's RBCS will be attacked by the mother's antibodies.
- the disease erythroblastosis fetalis develops in a fetus or a newborn infant with rh-positive blood and an rh-negative mother. symptoms result when maternal anti-rh antibodies cross the placenta and interact with the fetus' erythrocytes. what are the children of rh-positive mothers not at risk for this disease? why are rh-negative fetuses not at risk for this disease?In some cases of weak D antigen testing, the interpretation of results can reveal that the person tested is somewhat D+ and D- at the same time. How is this possible? What is/are the implication/s of this Rh phenotyping result in the blood donation and transfusion of the said person?A newborn has a positive DAT using anti-IgG AHG. An antibody screen is performed on the newborn's serum and is negative. The newborn forward types as A positive while the mother is O Positive. Explain two possibilities for this result. What is your next step?
- If antibody RH is given to a person with a B+ blood type what would happen? If antibody RH is given to a person with a A- blood type what would happen?You mix a few drops of a patient’s blood with ABO and Rh typing serums (antibodies against A, B, and Rh antigens), with these results: Anti-A: agglutination; Anti-B: no agglutination; Anti-Rh: agglutination. What is the patient’s ABO blood group and Rh type? A positive O negative O positive AB negative A negativeIn terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?
- Which of the following statements is NOT correct about the immunological incompatibility between mother and baby? Select one: a. The baby’s Rh+ blood will never get in contact with the mother’s Rh– blood during the pregnancy as the placenta does not allow fetal blood cells to mix with the maternal blood. b. When the mother has Rh– blood, anti-Rh antibody injection is given during her pregnancy to prevent any antibodies from forming. c. If the baby is Rh+ and the mother is Rh–, it does not pose a problem as long as this is the mother’s first pregnancy. d. Rh– blood has no rhesus factor proteins and therefore will produce antibodies for the Rh factor when exposed to Rh+ blood.Why do we have to repeat blood typing before proceeding to crossmatching proper? Is screening for Hepatitis B necessary before undergoing vaccination? Why?Why is it that Rh incompatibility can be a serious problem when anRh-negative mother is carrying an Rh-positive fetus, but ABOincompatibility between mother and fetus is usually no problem?That is, a type A mother can usually safely carry a type B fetus.(Hint: The antibodies produced by an Rh-negative mother againstthe Rh antigen are usually IgG, whereas the antibodies producedagainst the A or B antigens are IgM.) Because the Rh antigenobviously serves no vital function (most humans lack it), why do youthink it hasn’t been completely eliminated during human evolution?